Evidence map›Paper›PMID 36587367›Full record

ReviewEuropean journal of neurology2023

European Society for the Study of Tourette Syndrome 2022 criteria for clinical diagnosis of functional tic-like behaviours: International consensus from experts in tic disorders.

Tamara Pringsheim, Christos Ganos, Christelle Nilles, Andrea E Cavanna, Donald L Gilbert, Erica Greenberg, Andreas Hartmann, Tammy Hedderly, Isobel Heyman, Holan Liang and 14 more

Open access · greenAbstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in European journal of neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
20.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Update on the Pathophysiology and Management of Tics.Current neurology and neuroscience reports · 2026
    Review
  9. Article
  10. How do I Know That the Jerks I See Are Tics?Movement disorders clinical practice · 2025
    Review
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 17 institutions in 8 countries.

Tamara PringsheimDepartment of Clinical Neurosciences, Psychiatry, Pediatrics, and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-8229-8431
Christos GanosDepartment of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Christelle NillesDepartment of Clinical Neurosciences, Psychiatry, Pediatrics, and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Andrea E CavannaDepartment of Neuropsychiatry, Birmingham and Solihull Mental Health National Health Service Foundation Trust and University of Birmingham, Birmingham, UK.
Donald L GilbertDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Erica GreenbergDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-4127-7941
Andreas HartmannNational Reference Centre for Tourette Syndrome, Public Assistance Hospitals of Paris, Pitié-Salpêtrière Hospital Group, Paris, France.
Tammy HedderlyEvelina London Childrens Hospital, Guys and St Thomas Trust and Kings College London, London, UK.
Isobel HeymanUCL Great Ormond Street Institute of Child Health, London, UK.
Holan LiangUCL Great Ormond Street Institute of Child Health, London, UK.
Irene MalatyDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, Florida, USA.
Osman MalikDepartment of Children's Neuroscience, Evelina London Children's Hospital, Guys and St Thomas National Health Service Trust and South London and Maudsley National Health Service Trust, London, UK.
Nanette Mol DebesCopenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark.
Kirsten Muller VahlDepartment of Psychiatry, Social Psychiatry, and Psychotherapy, Hanover Medical School, Hanover, Germany.
Alexander MunchauInstitute of Systems Motor Science, University of Lübeck, Lübeck, Germany.
Tara MurphyUCL Great Ormond Street Institute of Child Health, London, UK.
Peter NagyDivision of Neurodevelopmental Disorders, Bethesda Children's Hospital, Budapest, Hungary.
Tamsin OwenEvelina London Childrens Hospital, Guys and St Thomas Trust and Kings College London, London, UK.
Renata RizzoChild and Adolescent Neurology and Psychiatry, Department of Clinical and Experimental Medicine, Catania University, Catania, Italy.
Liselotte SkovDepartment of Paediatrics, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark.
Jeremy SternDepartment of Neurology, St George's, University of London, London, UK.
Natalia SzejkoDepartment of Neurology, Department of Bioethics, Medical University of Warsaw, Warsaw, Poland.ORCID 0000-0001-6160-9221
Yulia WorbeDepartment of Neurophysiology, Assistance Publique-Hopitaux de Paris.6-Pitié-Salpêtrière and Saint Antoine Hospitals, Sorbonne University, Paris, France.
Davide MartinoDepartment of Clinical Neurosciences, Psychiatry, Pediatrics, and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-2217-0487
Great Ormond Street Hospital · GBUniversity of Calgary · CAKing's College London · GBNational Health Service · GBSorbonne Université · FRCharité - Universitätsmedizin Berlin · DECincinnati Children's Hospital Medical Center · USGentofte Hospital · DKMassachusetts General Hospital · USMedical University of Warsaw · PLMedizinische Hochschule Hannover · DENeuroDevelopment Center · USSt George's, University of London · GBUniversity of Catania · ITUniversity of Copenhagen · DKUniversity of Florida · USUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIn 2020, health professionals witnessed a dramatic increase in referrals of young people with rapid onset of severe tic-like behaviours. We assembled a working group to develop criteria for the clinical diagnosis of functional tic-like behaviours (FTLBs) to help neurologists, pediatricians, psychiatrists, and psychologists recognize and diagnose this condition.

methodsWe used a formal consensus development process, using a multiround, web-based Delphi survey. The survey was based on an in-person discussion at the European Society for the Study of Tourette Syndrome (ESSTS) meeting in Lausanne in June 2022. Members of an invited group with extensive clinical experience working with patients with Tourette syndrome and FTLBs discussed potential clinical criteria for diagnosis of FTLBs. An initial set of criteria were developed based on common clinical experiences and review of the literature on FTLBs and revised through iterative discussions, resulting in the survey items for voting.

resultsIn total, 24 members of the working group were invited to participate in the Delphi process. We propose that there are three major criteria and two minor criteria to support the clinical diagnosis of FTLBs. A clinically definite diagnosis of FTLBs can be confirmed by the presence of all three major criteria. A clinically probable diagnosis of FTLBs can be confirmed by the presence of two major criteria and one minor criterion.

conclusionsDistinguishing FTLBs from primary tics is important due to the distinct treatment paths required for these two conditions. A limitation of the ESSTS 2022 criteria is that they lack prospective testing of their sensitivity and specificity.

Indexed as

Tic DisordersTicsTourette SyndromeAdolescentHumansProspective Studiesfunctional neurological disorderticsTourette syndrome

Identifiers

PMID36587367
OpenAlexW4313379902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.