Observational studyJournal of perinatology : official journal of the California Perinatal Association2023
Increased risk of bradycardia in vigorous infants receiving early as compared to delayed cord clamping at birth.
Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Deferred cord clamping in twin pregnancies: benefit, risk, or missed opportunity? A narrative review.Resuscitation plus · 2026Review
- Observational
- Prevalence of bradycardia in 4876 newborns in the first minute after birth and association with positive pressure ventilation: a population-based cross-sectional study.Archives of disease in childhood. Fetal and neonatal edition · 2024Article
- Observational study comparing heart rate in crying and non-crying but breathing infants at birth.BMJ paediatrics open · 2023Observational
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveTo compare HR pattern of vigorous newborns during the first 180 s with early (≤60 s, ECC) or delayed (>60 s, DCC) cord clamping. STUDY
designObservational study including dry-electrode ECG monitoring of 610 vaginally-born singleton term and late-preterm (≥34 weeks) who were vigorous after birth.
results198 received ECC while 412 received DCC with median cord clamping at 37 s and 94 s. Median HR remained stable from 30 to 180 s with DCC (172 and 170 bpm respectively) but increased with ECC (169 and 184 bpm). The proportion with bradycardia was higher among ECC than DCC at 30 s and fell faster in the DCC through 60 s. After adjusting for factors affecting timing of cord clamping, ECC had significant risk of bradycardia compared to DCC (aRR 1.51; 95% CI; 1.01-2.26).
conclusionEarly heart instability and higher risk of bradycardia with ECC as compared to DCC supports the recommended clinical practice of DCC.
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