ArticleScientific reports2022
Development of a high-performance open-source 3D bioprinter.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- The Allstruder: an open syringe extruder for every 3D printer.HardwareX · 2026Article
- A one-step volumetric biofabrication platform for complex hydrogel-based hollow biomaterials.Materials today. Bio · 2026Article
- Support-Enabled 3D Printing of Complex Anisotropic Hydrogel Structures Using Cellulose-Based Inks: Pathways Toward Biomimetic Human Aorta Models.ACS biomaterials science & engineering · 2026Article
- The Promise of 3D Biomaterial Bioprinting for Wound-Healing and Skin Tissue Restoration.Life (Basel, Switzerland) · 2026Review
- Advances in extrusion-based bioprinting enabled by advanced printhead and nozzle designs.Materials today. Bio · 2026Review
- Clickable Microgel Inks Enable Spatioselective, Multi-Stimuli Programmable Assembly of Materials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A diffusion-based 3D printing strategy to fabricate self-supporting, perfusable networks.BMC methods · 2026Review
- High-throughput bioprinting to produce micropatterned neuroepithelial tissues and model TSC2-deficient brain malformations.Cell reports methods · 2025Article
- State of Research on Tissue Engineering with 3D Printing for Breast Reconstruction.Journal of clinical medicine · 2025Review
- Enhancing Bone Scaffold Fabrication: A Comparative Study of Manual Casting and Automated 3D Bioprinting.Annals of biomedical engineering · 2025Article
- Stem Cell Niche Concept: Search for Current Expert Consensus.International journal of molecular sciences · 2025Review
- Head and Neck 3D Bioprinting-A Review on Recent Advancements in Soft Tissue 3D Bioprinting and Medical Applications.Journal of functional biomaterials · 2025Review
- Enhancing Viability in Static and Perfused 3D Tissue Constructs Using Sacrificial Gelatin Microparticles.ACS biomaterials science & engineering · 2025Article
- 3D bioprinting of collagen-based high-resolution internally perfusable scaffolds for engineering fully biologic tissue systems.Science advances · 2025Article
- Extrusion bioprinting: meeting the promise of human tissue biofabrication?Progress in biomedical engineering (Bristol, England) · 2025Review
- A Low-Cost, Open-Source 3D Printer for Multimaterial and High-Throughput Direct Ink Writing of Soft and Living Materials.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Bioprinting and Intellectual Property: Challenges, Opportunities, and the Road Ahead.Bioengineering (Basel, Switzerland) · 2025Review
- FRESH 3D Bioprinting of Collagen Types I, II, and III.ACS biomaterials science & engineering · 2025Article
- The cutting-edge progress in bioprinting for biomedicine: principles, applications, and future perspectives.MedComm · 2024Review
- Dissecting the Interplay Mechanism among Process Parameters toward the Biofabrication of High-Quality Shapes in Embedded Bioprinting.Advanced functional materials · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The application of 3D printing to biological research has provided the tissue engineering community with a method for organizing cells and biological materials into complex 3D structures. While many commercial bioprinting platforms exist, they are expensive, ranging from $5000 to over $1,000,000. This high cost of entry prevents many labs from incorporating 3D bioprinting into their research. Due to the open-source nature of desktop plastic 3D printers, an alternative option has been to convert low-cost plastic printers into bioprinters. Several open-source modifications have been described, but there remains a need for a user-friendly, step-by-step guide for converting a thermoplastic printer into a bioprinter using components with validated performance. Here we convert a low-cost 3D printer, the FlashForge Finder, into a bioprinter using our Replistruder 4 syringe pump and the Duet3D Duet 2 WiFi for total cost of less than $900. We demonstrate that the accuracy of the bioprinter's travel is better than 35 µm in all three axes and quantify fidelity by printing square lattice collagen scaffolds with average errors less than 2%. We also show high fidelity reproduction of clinical-imaging data by printing a scaffold of a human ear using collagen bioink. Finally, to maximize accessibility and customizability, all components we have designed for the bioprinter conversion are provided as open-source 3D models, along with instructions for further modifying the bioprinter for additional use cases, resulting in a comprehensive guide for the bioprinting field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.