Evidence map›Paper›PMID 36586744›Full record

ReviewJournal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi2023

COVID-19 associated mold infections: Review of COVID-19 associated pulmonary aspergillosis and mucormycosis.

Shiang-Fen Huang, Alice Ying-Jung Wu, Susan Shin-Jung Lee, Yu-Shan Huang, Chun-Yuan Lee, Te-Liang Yang, Hsiao-Wei Wang, Hung Jui Chen, Yi Ching Chen, Tzong-Shiann Ho and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Unveiling the role of the respiratory microbiome in long COVID pathogenesis and therapeutics.Chinese medical journal pulmonary and critical care medicine · 2025
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  4. Article
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  6. Review
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  11. Review
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  15. Review
  16. Journal of fungi (Basel, Switzerland) · 2024
    Article
  17. Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Shiang-Fen HuangDivision of Infectious Disease, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; School of Internal Medicine, National Yang Ming Chao Tung University, Taipei, Taiwan. Electronic address: shuang6@vghtpe.gov.tw.
Alice Ying-Jung WuDivision of Infectious Diseases, Department of Medicine, MacKay Memorial Hospital, Taipei, Taiwan; MacKay Medical College, New Taipei City, Taiwan. Electronic address: watrlilies@gmail.com.
Susan Shin-Jung LeeSchool of Internal Medicine, National Yang Ming Chao Tung University, Taipei, Taiwan; Division of Infectious Disease, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Taiwan. Electronic address: ssjlee28@yahoo.com.tw.
Yu-Shan HuangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: b101091021@gmail.com.
Chun-Yuan LeeDivision of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; M.Sc. Program in Tropical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: leecy8801131@gmail.com.
Te-Liang YangDepartment of Pediatrics, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan; Department of Pediatrics, National Taiwan University Children's Hospital, Taipei, Taiwan. Electronic address: bowlingdy@gmail.com.
Hsiao-Wei WangDivision of Infectious Diseases, Department of Internal Medicine, Shin Kong Wu Ho- Su Memorial Hospital, Taipei, Taiwan. Electronic address: idwang6366@gmail.com.
Hung Jui ChenDepartment of Infectious Diseases, Chi-Mei Medical Center, Tainan, Taiwan. Electronic address: uolddy@gmail.com.
Yi Ching ChenDepartment of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address: cemily02@icloud.com.
Tzong-Shiann HoDepartment of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan; Department of Pediatrics, Tainan Hospital, Ministry of Health and Welfare, Tainan, Taiwan. Electronic address: tsho@mail.ncku.edu.tw.
Chien-Feng KuoDivision of Infectious Diseases, Department of Medicine, MacKay Memorial Hospital, Taipei, Taiwan; MacKay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan. Electronic address: kakutsai1230@gmail.com.
Yi-Tsung LinDivision of Infectious Disease, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Emergency and Critical Care Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address: ytlin8@vghtpe.gov.tw.
GREAT working group
National Yang Ming Chiao Tung University · TWMackay Memorial Hospital · TWNational Taiwan University Hospital · TWChang Gung Memorial Hospital · TWChi Mei Medical Center · TWKaohsiung Medical University · TWMemorial Hospital · USNational University of Tainan · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19-associated mold infection (CAMI) is defined as development of mold infections in COVID-19 patients. Co-pathogenesis of viral and fungal infections include the disruption of tissue barrier following SARS CoV-2 infection with the damage in the alveolar space, respiratory epithelium and endothelium injury and overwhelming inflammation and immune dysregulation during severe COVID-19. Other predisposing risk factors permissive to fungal infections during COVID-19 include the administration of immune modulators such as corticosteroids and IL-6 antagonist. COVID-19-associated pulmonary aspergillosis (CAPA) and COVID-19-associated mucormycosis (CAM) is increasingly reported during the COVID-19 pandemic. CAPA usually developed within the first month of COVID infection, and CAM frequently arose 10-15 days post diagnosis of COVID-19. Diagnosis is challenging and often indistinguishable during the cytokine storm in COVID-19, and several diagnostic criteria have been proposed. Development of CAPA and CAM is associated with a high mortality despiteappropriate anti-mold therapy. Both isavuconazole and amphotericin B can be used for treatment of CAPA and CAM; voriconazole is the primary agent for CAPA and posaconazole is an alternative for CAM. Aggressive surgery is recommended for CAM to improve patient survival. A high index of suspicion and timely and appropriate treatment is crucial to improve patient outcome.

Indexed as

COVID-19MucormycosisPulmonary AspergillosisFungiHumansPandemicsAspergillosisCAMCAPACOVID-19Mucormycosis

Identifiers

PMID36586744
PMCPMC9751001
OpenAlexW4311512137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.