Evidence map›Paper›PMID 36586074›Full record

ArticleSleep & breathing = Schlaf & Atmung2023

Relationship between slow-wave sleep and serum γ-glutamine transaminase in non-obese men with obstructive sleep apnea-hypopnea syndrome.

Qiyuan Pan, Hanqing Li, Xieyu Gan, Xin Chen, Xirui Liu, Jinfang Li

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qiyuan PanDepartment of Neurology,  The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Hanqing LiDepartment of Stomatology, The First People's Hospital of Zaoyang City, 441200, Hubei Province, China.
Xieyu GanDepartment of Neurology,  The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Xin ChenDepartment of Neurology,  The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Xirui LiuDepartment of Neurology,  The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Jinfang LiDepartment of Neurology,  The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. lijinfang@hospital.cqmu.edu.cn.ORCID 0000-0002-0689-440X
Dalian Medical University · CNFirst People's Hospital of Nanning · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObstructive sleep apnea-hypopnea syndrome (OSAHS) is a disease characterized with intermittent hypoxia and sleep fragmentation. Obesity and gender are major risk factors for the onset of OSAHS. Previous studies on obese men with OSAHS have been performed, while few studies on non-obese men with OSAHS have been carried out. The purpose of this study was to explore the clinical characteristics of polysomnography and blood biochemical indexes in non-obese men with OSAHS and to identify the possible influencing factors.

methodsThis retrospective study included patients with OSAHS who underwent polysomnography in our hospital. General clinical data such as overnight polysomnography and biochemical indicators were recorded. The patients were divided into two groups according to the apnea-hypopnea index (AHI): mild to moderate OSAHS and severe OSAHS. The differences in biochemical parameters such as the levels of γ-glutamine transaminase (GGT), triglyceride (TG), glucose (GLU), and sleep structure parameters such as N1, N2, slow-wave sleep (SWS), and rapid eye movement (REM) sleep were compared and analyzed. Spearman correlation analysis and logistic regression were used to identify the risk factors of non-obese men with OSAHS. ROC curves were used to evaluate the predictive ability of SWS and GGT on disease severity.

resultsOf 94 non-obese men with OSAHS, 49 had mild to moderate OSAHS and 45 had severe OSAHS. Our data suggested that the levels of low oxygen saturation (L-SaO

conclusionsThese results suggest that SWS and GGT are independent associated factors of the severity of the disease. However, TyG index was not an independent associated factor of the severity of disease in non-obese men with OSAHS. In addition, SWS and GGT were negatively correlated. SWS combined with serum GGT may be predictive of the severity of the disease. This study may have added to our understanding of the pathogenesis of OSAHS in non-obese men.

Indexed as

Sleep Apnea, ObstructiveSleep, Slow-Wavegamma-GlutamyltransferaseGlucoseHumansMaleObesityRetrospective StudiesSyndromeTransaminasesgamma-Glutamyltransferasegamma-glutamyltransferase, humanGlucoseglutamine-pyruvate aminotransferaseTransaminasesObstructive sleep apnea–hypopnea syndromeSlow-wave sleepTriglyceride-glucose indexγ-glutamyl transferase

Identifiers

PMID36586074
OpenAlexW4313339599

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.