Evidence map›Paper›PMID 36585857›Full record

ArticleThyroid : official journal of the American Thyroid Association2023

Inhibition of ALK-Signaling Overcomes STRN-ALK-Induced Downregulation of the Sodium Iodine Symporter and Restores Radioiodine Uptake in Thyroid Cells.

Alyaksandr V Nikitski, Vincenzo Condello, Saurabh S Divakaran, Yuri E Nikiforov

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Evolving trends in pediatric thyroid nodules and cancer management.Annals of pediatric endocrinology & metabolism · 2026
    Article
  4. Article
  5. Article
  6. MicroRNAs and Their Inhibition in ModulatingInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Positron emission tomography probes for stem cell monitoring: a review.American journal of translational research · 2024
    Review
  17. The Evolving Genomic Landscape of Pediatric Papillary Thyroid Cancer.Current opinion in endocrine and metabolic research · 2023
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alyaksandr V NikitskiDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6486-667X
Vincenzo CondelloDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Saurabh S DivakaranDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Yuri E NikiforovDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-2239-1095
University of Pittsburgh · US

Funding

ALK Rearrangements in Aggressive Thyroid CancerR01CA181150 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NIKIFOROV, YURI E · 2014 to 2024
$3.3M
NCI NIH HHS R01 CA181150
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

SymportersThyroid NeoplasmsCalmodulin-Binding ProteinsCrizotinibDown-RegulationHumansIodine RadioisotopesMembrane ProteinsMonocarboxylic Acid TransportersNerve Tissue ProteinsNitrilesPhosphatidylinositol 3-KinasesPyrazolesPyrimidinesReceptor Protein-Tyrosine KinasesSodiumCalmodulin-Binding ProteinsceritinibCrizotinibIodine RadioisotopesMembrane ProteinsMonocarboxylic Acid TransportersNerve Tissue ProteinsNitrilesPhosphatidylinositol 3-KinasesPyrazolesPyrimidinesReceptor Protein-Tyrosine KinasesruxolitinibSLC5A8 protein, humanSodiumSTRN protein, humanSulfonesSymportersredifferentiationsodium iodine symporterSTRN-ALKthyroid

Identifiers

PMID36585857
PMCPMC10122237
OpenAlexW4313323884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.