Evidence map›Paper›PMID 36585795›Full record

SynthesisOrthopaedic surgery2023

Is Patient-Specific Instrumentation Accurate and Necessary for Open-Wedge High Tibial Osteotomy? A Meta-Analysis.

Ran Pang, Zhaohui Jiang, Chunlei Xu, Wei Shi, Xinglong Zhang, Xin Wan, Daniel Bahat, Hui Li, Fedor Senatov, Inna Bulygina and 3 more

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Orthopaedic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07212777 (Precisión de la osteotomía Tibial Proximal Con Instrumental Paciente-específico vs técnica Convencional), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07212777 narecruitingnot on this mapstarted 2025, after this paper: background citation

Precisión de la osteotomía Tibial Proximal Con Instrumental Paciente-específico vs técnica Convencional

TypeinterventionalSponsorUniversity of MalagaRan2025 to 2028Enrolled50ConditionsArthritis (Knee), Varus KneeArmsMedial Open Wedge Hight Tibial Osteotomy using patient-specific instrumentation, Medial Open Wedge Hight Tibial Osteotomy using conventional surgery techniques
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. [Clinical application research of three-dimensional printed patient-specific cutting guides in Cole midfoot osteotomy].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Article
  5. Article
  6. Review
  7. Accuracy of medial opening wedge high tibial osteotomy using patient-specific instrumentation: a randomised cadaveric study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ran Pang *Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.ORCID https://orcid.org/0000-0002-4671-6018
Zhaohui Jiang *Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.
Chunlei XuDepartment of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.
Wei ShiDepartment of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.
Xinglong ZhangDepartment of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.
Xin WanDepartment of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.
Daniel BahatDepartment of Orthopaedics, Cleveland Clinic, Cleveland, Ohio, USA.
Hui LiDepartment of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.
Fedor SenatovCenter for Biomedical Engineering, National University of Science and Technology "MISIS", Moscow, Russia.
Inna BulyginaCenter for Biomedical Engineering, National University of Science and Technology "MISIS", Moscow, Russia.
Hu WangDepartment of Physical Health Care and Rehabilitation, Tianjin Vocational College of Sports, Tianjin, PR China.
Huafeng ZhangDepartment of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.
Zhijun LiDepartment of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, PR China.ORCID https://orcid.org/0000-0002-3415-9461

Funding

National Natural Science Foundation of China 81701193The Key Scientific Project of Tianjin Sports Bureau 21BZ002
6 · The paper itself

Abstract

The purpose of this meta-analysis was to identify if patient-specific instrumentation (PSI) could increase the accuracy of the correction in high tibial osteotomy (HTO) and to explore the assessment indices and the necessity of using a PSI in HTO. A systematic search was carried out using online databases. A total of 466 patients were included in 11 papers that matched the inclusion criteria. To evaluate the accuracy of PSI-assisted HTO, the weight bearing line ratio (WBL%), hip-knee-ankle angle (HKA), mechanical medial proximal tibial angle (mMPTA), and posterior tibial slope angle (PTSA) were measured preoperatively and postoperatively and compared to the designed target values. Statistical analysis was performed after strict data extraction with Review Manager (version 5.4). Significant differences were detected in WBL% (MD = -36.41; 95% CI: -42.30 to -30.53; p < 0.00001), HKA (MD = -9.95; 95% CI: -11.65 to -8.25; p < 0.00001), and mMPTA (MD = -8.40; 95% CI:-10.27 to -6.53; p < 0.00001) but not in PTSA (MD = 0.34; 95% CI: -0.59 to 1.27; p = 0.47) between preoperative and postoperative measurements. There was no significant difference between the designed target values and the postoperative correction values of HKA (MD = 0.14; 95% CI: -0.19 to 0.47; p = 0.41) or mMPTA (MD = 0.11; 95% CI -0.34 to 0.55; p = 0.64). The data show that 3D-based planning of PSI for HTO is both accurate and safe. WBL%, HKA, and mMPTA were the optimal evaluation indicators of coronal plane correction. Sagittal correction is best evaluated by the PTSA. The present study reports that PSI is accurate but not necessary in typical HTO.

Indexed as

Osteoarthritis, KneeHumansKnee JointOsteotomyPyrenesRetrospective StudiesTibia1,3,6,8-pyrene tetrasulfonatePyrenesHigh tibial osteotomyMeta-analysisOsteoarthritisPatient-specific cutting guidesPatient-specific instrumentationThree-dimensional

Identifiers

PMID36585795
PMCPMC9891955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.