Evidence map›Paper›PMID 36585623›Full record

Trial reportBMC surgery2022

Perioperative pectoral nerve block type II and postoperative recurrence in breast cancer: a randomized controlled trial.

Lili Yu, Xiuling Cui, Panpan Song, Chunlei Li, Haochen Zhao, Yulin Chang

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lili YuDepartment of Anesthesiology, Cangzhou Central Hospital, No.16, Xinhua Road, Cangzhou, 061000, Hebei, China. 18713057030@163.com.
Xiuling CuiDepartment of Anesthesiology, Cangzhou Central Hospital, No.16, Xinhua Road, Cangzhou, 061000, Hebei, China.
Panpan SongDepartment of Anesthesiology, Cangzhou Central Hospital, No.16, Xinhua Road, Cangzhou, 061000, Hebei, China.
Chunlei LiDepartment of Anesthesiology, Cangzhou Central Hospital, No.16, Xinhua Road, Cangzhou, 061000, Hebei, China.
Haochen ZhaoDepartment of Anesthesiology, Cangzhou Central Hospital, No.16, Xinhua Road, Cangzhou, 061000, Hebei, China.
Yulin ChangDepartment of Anesthesiology, Cangzhou Central Hospital, No.16, Xinhua Road, Cangzhou, 061000, Hebei, China.
Cangzhou Central Hospital · CN

Funding

Hebei Cangzhou Guidance Project of Key R&D Program of China 204106120
6 · The paper itself

Abstract

backgroundA new technique for analgesia called pectoral nerve block is widely used in surgeries of breast cancer. Pectoral nerve block type II (Pecs II) block has less influence on immunity when compared with general anesthesia method. The purpose of this research is to demonstrate whether Pecs II block has influence on the recurrence of breast cancer after surgical operation.

methods526 breast cancer patients were recruited in this research and randomized into general anesthesia group and general anesthesia with Pecs II block group. Recurrence-free survival (RFS), distant recurrence-free survival (DRFS), and overall survival (OS) were evaluated for the two groups.

resultsBased on the statistical data, only the consumption of remifentanil was dramatically reduced by the performance of Pecs II block when compared with general anesthesia method. The performance of Pecs II block had no significant influence on OS, RFS, and DRFS of breast cancer patients after surgery. ASA physical status III, TNM stage 2 + 3, and mastectomy were proved to have association with lower recurrence-free survival.

conclusionIn conclusion, the performance of Pecs II block declined the remifentanil consumption during surgery of breast cancer. Meanwhile, the performance of Pecs II block had no significant influence on the OS, RFS, and DRFS of breast cancer patients after surgical resection.

Indexed as

Breast NeoplasmsThoracic NervesFemaleHumansMastectomyNeoplasm Recurrence, LocalPostoperative PainRemifentanilRemifentanilBreast cancerPectoral nerve block type IIPostoperative recurrence

Identifiers

PMID36585623
PMCPMC9805115
OpenAlexW4313303951

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.