Evidence map›Paper›PMID 36585556›Full record

ArticlePulmonary therapy2023

Autologous Blood Patch Pleurodesis for Secondary Spontaneous Pneumothorax: A Narrative Review, a Retrospective Case Series and State of Play in the UK.

Sufyan Shakir, Brian Choo-Kang, Clare Ross, Kevin Conroy, Richard Thorley, Steven Walker, Rahul Bhatnagar, Avinash Aujayeb

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. New strategies in the management of pneumothorax.Breathe (Sheffield, England) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Sufyan ShakirDepartment of Respiratory Medicine, Northumbria Healthcare NHS Trust, Northumbria Way, Cramlington, NE23 6NZ, UK.
Brian Choo-KangDepartment of Respiratory Medicine, Glasgow Royal Infirmary, 84 Castle Street, Glasgow, G4 0SF, UK.
Clare RossImperial College NHS Trust, Exhibition Rd, South Kensington, London, SW7 2BX, UK.
Kevin ConroyNorth Tees and Hartlepool NHS Foundation Trust, University Hospital of North Tees, Hardwick Road, Stockton On Tees, Cleveland, TS19 8PE, UK.
Richard ThorleyDepartement of Respiratory Medicine, North Devon District Hospital, Raleigh Heights, Barnstaple, EX31 4JB, UK.
Steven WalkerAcademic Respiratory Unit, 2nd Floor, Learning and Research, Southmead Hospital, Westbury-On-Trym, Bristol, BS10 5NB, UK.
Rahul BhatnagarAcademic Respiratory Unit, 2nd Floor, Learning and Research, Southmead Hospital, Westbury-On-Trym, Bristol, BS10 5NB, UK.
Avinash AujayebDepartment of Respiratory Medicine, Northumbria Healthcare NHS Trust, Northumbria Way, Cramlington, NE23 6NZ, UK. avinash.aujayeb@nhct.nhs.uk.ORCID http://orcid.org/0000-0002-0859-5550
Northumbria Healthcare NHS Foundation Trust · GBSouthmead Hospital · GBGlasgow Royal Infirmary · GBImperial College London · GBNorth Devon District Hospital · GBNorth Tees and Hartlepool NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTreatment of prolonged air leak due to secondary spontaneous pneumothorax is challenging. Autologous blood patch pleurodesis (ABPP) is a treatment option. Previous evidence is reliant on single-centre series and underpowered trials and is mostly described in air leaks post cardiothoracic intervention. There are no United Kingdom (UK) wide data.

methodsMembers of the UK Pleural Society were surveyed for their practice and for patients who underwent blood patch. There were 16 respondents from 333 members. Twelve had performed the procedure, and six had kept records and could submit data. Basic demographics, intervention and clinical details of patients were then collected. The study was sponsored by the Audit Department of Northumbria Healthcare NHS Foundation Trust (reference 8124), and Caldicott Clearance for data sharing was provided by the Trust's Information Goverance Board (reference C4221). There was no requirement for informed consent.

resultsData for 12 patients that received ABPP between 2014 and 2022 in six respiratory centres were assessed. The aetiology of the secondary pneumothoraces was mostly due to chronic obstructive pulmonary disease and end-stage interstitial lung disease. The patients had a median age of 75 years. The median air leak time before ABPP was 17 days. A total of 50-100 ml of blood was used for ABPP. Five patients had two attempts at ABPP. Air leak resolved in six patients (50%). Four patients had pleural apposition prior to ABPP. Four patients were diagnosed with hospital-acquired pneumonia following ABPP.

conclusionThis is the only UK-wide retrospective case series of ABPP of 'medical' patients with secondary pneumothorax. There is widespread variation in care. No formal conclusions can be drawn, and much larger robust datasets are required. An application has been made to the European Respiratory Society to incorporate ABPP within the International Collaborative Effusion database.

Indexed as

Autologous blood patchBlood patchPleurodesisPneumothorax

Identifiers

PMID36585556
PMCPMC9931973
OpenAlexW4313339942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.