Evidence map›Paper›PMID 36585451›Full record

ArticleNature cancer2023

HDAC6 score: to treat or not to treat?

Joschka Hey, Maria Llamazares Prada, Christoph Plass

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. MYC as a key target for melanoma therapy.Frontiers in cell and developmental biology · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Joschka HeyDivision of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Maria Llamazares PradaDivision of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Christoph PlassDivision of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany. c.plass@dkfz.de.ORCID http://orcid.org/0000-0003-2554-3952

Funding

Systematic Identification and Pharmacological Targeting of Tumor Dependencies for Precision Cancer MedicineU01CA217858 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CALIFANO, ANDREA · 2017 to 2021
$6.1M
High-performance compute cluster for biomedical computingS10OD012351 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CALIFANO, ANDREA · 2012 to 2012
$2.0M
Non-cancer gene addition as anticancer strategyR01CA153233 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SILVA, JOSE M · 2010 to 2012
$786k
Storage System for High Performance ComputingS10OD021764 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CALIFANO, ANDREA · 2016 to 2016
$600k
NCI NIH HHS R01 CA153233NCI NIH HHS U01 CA217858NIH HHS S10 OD012351NIH HHS S10 OD021764
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Histone DeacetylasesHistone Deacetylase 6Histone Deacetylase 6Histone Deacetylases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.