Evidence map›Paper›PMID 36585436›Full record

Trial reportScientific reports2022

Modulating mental state recognition by anodal tDCS over the cerebellum.

Silvia Clausi, Michela Lupo, Giulia Funghi, Alessia Mammone, Maria Leggio

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Cerebellar tDCS Modulates Corticocortical Functional Networks in a Regionally Specific Manner.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Review
  5. Review
  6. Social and emotional learning in the cerebellum.Nature reviews. Neuroscience · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Silvia ClausiAtaxia Laboratory, Fondazione Santa Lucia IRCCS, Via Ardeatina, 306, Rome, Italy. silvia.clausi@gmail.com.
Michela LupoAtaxia Laboratory, Fondazione Santa Lucia IRCCS, Via Ardeatina, 306, Rome, Italy.
Giulia FunghiCenter for Mind/Brain Sciences CIMeC, University of Trento, Corso Bettini, 31, Rovereto, Italy.
Alessia MammoneNational Institute for Infectious Diseases Lazzaro Spallanzani - IRCSS, Via Portuense, 292, Rome, Italy.
Maria LeggioAtaxia Laboratory, Fondazione Santa Lucia IRCCS, Via Ardeatina, 306, Rome, Italy.
Fondazione Santa Lucia · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITUniversity of Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence from neuroimaging and clinical studies has demonstrated cerebellar involvement in social cognition components, including the mentalizing process. The aim of this study was to apply transcranial direct current stimulation (tDCS) to modulate cerebellar excitability to investigate the role the cerebellum plays in mental state recognition. Forty-eight healthy subjects were randomly assigned to different groups in which anodal, cathodal, or sham tDCS (2 mA for 20 min) was delivered centering the electrode on the vermis to stimulate the posterior portion of the cerebellum. The ability to attribute mental states to others was tested before and after tDCS using a digital version of the 'Reading the Mind in the Eyes test', which includes visual perceptive and motor stimuli as control conditions. Correct response and reaction times (RTs) were recorded. The results revealed a significant reduction in RTs between the baseline and post-stimulation sessions after cerebellar anodal tDCS only for mental state stimuli (Wilcoxon test p = 0.00055), whereas no significant effect was found in the cathodal or sham conditions or for visual perceptive and motor stimuli. Overall, our study suggests that cerebellar anodal tDCS might selectively improve mental state recognition and constitute an effective strategy to positively modulate the mentalizing process.

Indexed as

Transcranial Direct Current StimulationCerebellumElectrodesHumansReaction Time

Identifiers

PMID36585436
PMCPMC9803656
OpenAlexW4313366979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.