Evidence map›Paper›PMID 36585380›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Two-Photon Polymerization: Fundamentals, Materials, and Chemical Modification Strategies.

Seán O'Halloran, Abhay Pandit, Andreas Heise, Andrew Kellett

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Panchromatic Photocatalysis using a Ruthenium Polypyridyl Complex.Journal of the American Chemical Society · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Exploiting Device Deformability for Fluid and Particle Manipulation.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  12. Article
  13. Review
  14. Article
  15. Amplified Spontaneous Emission Enhancement in FAPbIACS applied materials & interfaces · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seán O'HalloranCÚRAM, the SFI Research Centre for Medical Devices, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland.ORCID https://orcid.org/0000-0002-8312-6420
Abhay PanditCÚRAM, the SFI Research Centre for Medical Devices, University of Galway, Galway, H91 W2TY, Ireland.ORCID https://orcid.org/0000-0002-6292-4933
Andreas HeiseRCSI, University of Medicine and Health Sciences, Department of Chemistry, 123 St. Stephens Green, Dublin, Dublin 2, Ireland.ORCID https://orcid.org/0000-0001-5916-8500
Andrew KellettCÚRAM, the SFI Research Centre for Medical Devices, School of Chemical Sciences, Dublin City University, Glasnevin, Dublin 9, Ireland.ORCID https://orcid.org/0000-0002-8947-1401

Funding

European Union Horizon 2020 Marie Skłodowska-Curie (NATURE-ETN) 861381Irish Research Council IRCLA/2022/3815Science Foundation Ireland 12/RC/2275_P2Science Foundation Ireland 13/RC/2073_2Science Foundation Ireland 17/RC-PhD/3480
6 · The paper itself

Abstract

Two-photon polymerization (TPP) has become a premier state-of-the-art method for microscale fabrication of bespoke polymeric devices and surfaces. With applications ranging from the production of optical, drug delivery, tissue engineering, and microfluidic devices, TPP has grown immensely in the past two decades. Significantly, the field has expanded from standard acrylate- and epoxy-based photoresists to custom formulated monomers designed to change the hydrophilicity, surface chemistry, mechanical properties, and more of the resulting structures. This review explains the essentials of TPP, from its initial conception through to standard operating principles and advanced chemical modification strategies for TPP materials. At the outset, the fundamental chemistries of radical and cationic polymerization are described, along with strategies used to tailor mechanical and functional properties. This review then describes TPP systems and introduces an array of commonly used photoresists including hard polyacrylic resins, soft hydrogel acrylic esters, epoxides, and organic/inorganic hybrid materials. Specific examples of each class-including chemically modified photoresists-are described to inform the understanding of their applications to the fields of tissue-engineering scaffolds, micromedical, optical, and drug delivery devices.

Indexed as

3D laser printingdirect laser writingmodification strategiesphotoresiststwo-photon polymerization

Identifiers

PMID36585380
PMCPMC9982557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.