Evidence map›Paper›PMID 36585031›Full record

ReviewBMJ global health2022

Sudan virus disease outbreak in Uganda: urgent research gaps.

Susan Khader Ibrahim, Duduzile Edith Ndwandwe, Katherina Thomas, Louise Sigfrid, Alice Norton

Abstract readReview
In one paragraph

Review in BMJ global health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
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  4. CD4Nature immunology · 2026
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  17. Design of universal Ebola virus vaccine candidates via immunofocusing.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Article
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  20. Design of universal Ebola virus vaccine candidatesbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Susan Khader IbrahimGloPID-R Research and Policy Team, Pandemic Sciences Institute, University of Oxford, Oxford, UK.ORCID 0000-0002-2078-0097
Duduzile Edith NdwandweCochrane South Africa, South African Medical Research Council, Cape Town, South Africa.
Katherina ThomasWalimu, NGO, Kampala, Uganda.
Louise SigfridGloPID-R Research and Policy Team, Pandemic Sciences Institute, University of Oxford, Oxford, UK louise.sigfrid@gmail.com.ORCID 0000-0003-2764-1177
Alice NortonGloPID-R Research and Policy Team, Pandemic Sciences Institute, University of Oxford, Oxford, UK.

Funding

Wellcome TrustWellcome Trust 215091/Z/18/Z
6 · The paper itself

Abstract

The Sudan ebolavirus (SUDV) outbreak highlights our ongoing vulnerability to re-emerging high-consequence infectious diseases. Although the Minister of health in Uganda has initiated public health measures in collaboration with neighbouring countries and with support of the WHO, cases have continued to spread to several regions including the capital. The ongoing transmission, uncertain case numbers and no licensed vaccine or therapeutics available are a cause for concern. We searched four databases for SUDV research using the search terms "SUDV", "Sudan Virus" and "Ebola Sudan". Our analysis identified only 20 SUDV research studies. Most were implemented in the USA and only one in Uganda. Nine studies were on therapeutics, eight on vaccines, one on diagnostics, one in one health and one in social science. Our data highlight a lack of SUDV research and an urgent need for investment to identify an effective vaccine, and optimal supportive care and therapeutic strategies for all at risk groups as a key research priority. Research investments should be prioritised into vaccines and treatment strategies that will be accessible to high-risk populations in affected regions during the outbreak, to protect populations, improve individual outcomes and facilitate outbreak control.

Indexed as

Evidence GapsHemorrhagic Fever, EbolaAntibodies, ViralDisease OutbreaksHumansUgandaAntibodies, ViralInfections, diseases, disorders, injuriesPublic HealthReviewViral haemorrhagic fevers

Identifiers

PMID36585031
PMCPMC9809242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.