ArticleEnvironmental research2023
Short-term associations between warm-season ambient temperature and emergency department visits for Alzheimer's disease and related dementia in five US states.
Article in Environmental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Climate Change and Extreme Weather Event Adaptations for Individuals With Dementia: A Systematic Review.Brain and behavior · 2026Pooled it
- Green spaces, blue spaces and human health: an updated umbrella review of epidemiological meta-analyses.Frontiers in public health · 2025Pooled it
- Effects of ambient temperature on mental and neurological conditions in older adults: A systematic review and meta-analysis.Environment international · 2024Pooled it
- Practical considerations for characterization of the external exposome in Alzheimer's disease and related dementias cohorts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Effects of natural disasters on the cognitive state of older adults with dementia: a scoping review.European geriatric medicine · 2026Article
- Weather information improves a predictive model of emergency department arrivals.Internal and emergency medicine · 2026Article
- Long-term temperature variability and cognitive performance among mid-to-older-aged adults in China.Scientific reports · 2026Article
- Temperature discomfort impairs everyday cognition: a pilot study using smartwatch-based ecological momentary assessment.Environmental research communications · 2026Article
- Short-term effects and attributable burden of extreme heat and cold on dementia mortality: a case-time-series study in Hebei Province, China (2014-2022).BMC public health · 2026Article
- Combined and synergistic effects of heat and fine particulate matter on hospitalization among patients with Alzheimer's disease and related dementias.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Environmental Stressors and Neuroinflammation: Linking Climate Change to Alzheimer's Disease.Current issues in molecular biology · 2025Review
- Dual-mode nanozyme-hydrogel platform for on-site multi-target detection of biomarkers and hazardous substances.Mikrochimica acta · 2025Article
- Effects of ambient temperature on hospital admissions and mortality among older adults with and without dementia in South Korea.International journal of epidemiology · 2025Article
- Estimating Heterogeneous Exposure Effects in the Case-Crossover Design using BART.Journal of the American Statistical Association · 2025Article
- Associations Between Temperature and Location of Injury or Condition Among Heat-Related Emergency Department Visits.GeoHealth · 2025Article
- Impact of Heat on Respiratory Hospitalizations among Older Adults in 120 Large U.S. Urban Areas.Annals of the American Thoracic Society · 2025Article
- Investigating effects of air quality and weather on brain volumes.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- Elevated Ambient Temperature Associated With Increased Cardiovascular Disease-Risk Among Patients on Hemodialysis.Kidney international reports · 2024Article
- Heat Exposure and Dementia-Related Mortality in China.JAMA network open · 2024Article
- Environmental risk factors provoke new thinking for prevention and treatment of dementia with Lewy bodies.Heliyon · 2024Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundAmbient temperatures are projected to increase in the future due to climate change. Alzheimer's disease (AD) and Alzheimer's disease-related dementia (ADRD) affect millions of individuals and represent substantial health burdens in the US. High temperature may be a risk factor for AD/ADRD outcomes with several recent studies reporting associations between temperature and AD mortality. However, the link between heat and AD morbidity is poorly understood.
methodsWe examined short-term associations between warm-season daily ambient temperature and AD/ADRD emergency department (ED) visits for individuals aged 45 years or above during the warm season (May to October) for up to 14 years (2005-2018) in five US states: California, Missouri, North Carolina, New Jersey, and New York. Daily ZIP code-level maximum, average and minimum temperature exposures were derived from 1 km gridded Daymet products. Associations are assessed using a time-stratified case-crossover design using conditional logistic regression.
resultsWe found consistent positive short-term effects of ambient temperature among 3.4 million AD/ADRD ED visits across five states. An increase of the 3-day cumulative temperature exposure of daily average temperature from the 50th to the 95th percentile was associated with a pooled odds ratio of 1.042 (95% CI: 1.034, 1.051) for AD/ADRD ED visits. We observed evidence of the association being stronger for patients 65-74 years of age and for ED visits that led to hospital admissions. Temperature associations were also stronger among AD/ADRD ED visits compared to ED visits for other reasons, particularly among patients aged 65-74 years.
conclusionPeople with AD/ADRD may represent a vulnerable population affected by short-term exposure to high temperature. Our results support the development of targeted strategies to reduce heat-related AD/ADRD morbidity in the context of global warming.
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