Evidence map›Paper›PMID 36584703›Full record

ArticleJournal of affective disorders2023

Clinical characteristics, impairment, and psychiatric morbidity in 102 youth with misophonia.

Andrew G Guzick, Matti Cervin, Eleanor E A Smith, Jane Clinger, Isabel Draper, Wayne K Goodman, Marijn Lijffijt, Nicholas Murphy, Adam B Lewin, Sophie C Schneider and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Andrew G GuzickDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States. Electronic address: andrew.guzick@bcm.edu.
Matti CervinDepartment of Clinical Sciences Lund, Lund University, Sweden.
Eleanor E A SmithDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States.
Jane ClingerDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States.
Isabel DraperDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States.
Wayne K GoodmanDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States.
Marijn LijffijtDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States.
Nicholas MurphyDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States.
Adam B LewinDepartment of Pediatrics, University of South Florida, United States.
Sophie C SchneiderDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States.
Eric A StorchDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, United States.
Baylor College of Medicine · USLund University · SEUniversity of South Florida · US

Funding

Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MIRJANA MALETIC-SAVATIC · 2020 to 2026
$9.9M
Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, SAMACO, RODNEY C · 2014 to 2019
$7.8M
NICHD NIH HHS P50 HD103555NICHD NIH HHS U54 HD083092
6 · The paper itself

Abstract

backgroundThere is little information on the clinical presentation, functional impact, and psychiatric characteristics of misophonia in youth, an increasingly recognized syndrome characterized by high emotional reactivity to certain sounds and associated visual stimuli.

methodOne-hundred-two youth (8-17 years-old) with misophonia and their parents were recruited and compared with 94 youth with anxiety disorders. Participants completed validated assessments of misophonia severity, quality of life, as well as psychiatric symptoms and diagnoses.

resultsThe most common misophonia triggers included eating (96 %), breathing (84 %), throat sounds (66 %), and tapping (54 %). Annoyance/irritation, verbal aggression, avoidance behavior, and family impact were nearly universal. Misophonia severity was associated with internalizing symptoms, child-reported externalizing behaviors, and poorer quality of life. High rates of comorbidity with internalizing and neurodevelopmental disorders were found. Quality of life and externalizing behaviors were not significantly different between misophonia and anxiety samples; internalizing symptoms and autism characteristics were significantly higher among youth with anxiety disorders. LIMITATIONS: This self-selected sample was characterized by limited multicultural diversity.

conclusionsThis study presents misophonia as a highly impairing psychiatric syndrome. Future interdisciplinary work should clarify the mechanisms of misophonia, establish evidence-based treatments, and extend these findings to randomly sampled and more culturally diverse populations.

Indexed as

Hearing DisordersQuality of LifeAdolescentAnxiety DisordersChildHumansMorbiditySyndromeAdolescentsAssessmentChildrenComorbidityPhenomenologySensory sensitivityTreatment

Identifiers

PMID36584703
PMCPMC9878468
OpenAlexW4313339632

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.