Evidence map›Paper›PMID 36584621›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2023

IPVS policy statement on HPV nucleic acid testing guidance for those utilising/considering HPV as primary precancer screening: Quality assurance and quality control issues.

Suzanne M Garland, Thomas Iftner, Kate Cuschieri, Andreas M Kaufmann, Marc Arbyn, Silvia de Sanjose, Mario Poljak, Joakim Dillner, Elizabeth R Unger, IPVS Policy Committee

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Improved cervical screening using HPV type restriction and cycle threshold limit setting with the AmpFire assay: A prospective screening cohort of women with and without HIV in Botswana.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Suzanne M GarlandDepartment of Obstetrics and Gynaecology, University of Melbourne, Parkville 3052, Victoria, Australia; Centre for Women's Infectious Diseases Research, The Royal Women's Hospital, Parkville 3052, Victoria, Australia; Infection and Immunity, Murdoch Children's Research Institute, Parkville 3052, Victoria, Australia. Electronic address: suzanneg@unimelb.edu.au.
Thomas IftnerInstitute Med. Virology and Epidemiology, of Viral Diseases Institut Med. Virologie und Epidemiologie der Viruskrankheiten Elfriede-Aulhorn-Str. 6| 72076 Tübingen, Germany.
Kate CuschieriScottish HPV Reference Laboratory, Royal Infirmary of Edinburgh, Edinburgh, Scotland; HPV Research Group, University of Edinburgh, Edinburgh, Scotland.
Andreas M KaufmannCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Clinic for Gynecology, Augustenburger Platz 1, 13353, Berlin, Germany.
Marc ArbynUnit Cancer Epidemiology, Belgian Cancer Centre, Sciensano, 1050 Brussels, Belgium.
Silvia de SanjoseISGlobal, Barcelona, Spain.
Mario PoljakInstitute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia.
Joakim DillnerMedical Diagnostics Karolinska| Karolinska University Hospital, Center for Cervical Cancer Prevention, 14186 Stockholm, Sweden.
Elizabeth R UngerDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta GA, USA.
IPVS Policy Committee
Barcelona Institute for Global Health · ESUniversity of Ljubljana · SI

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

We advise that only clinically validated HPV assays which have fulfilled internationally accepted performance criteria be used for primary cervical screening. Further, assays should be demonstrated to be fit for purpose in the laboratory in which they will ultimately be performed, and quality materials manuals and frameworks will be helpful in this endeavor. Importantly, there is a fundamental shortage of well validated, low-cost, low complexity HPV tests that have demonstrated utility in a near-patient setting; representing a significant challenge and focus for future development in order to reach the WHO's goal of eliminating cervical cancer.

Indexed as

Nucleic AcidsPapillomavirus InfectionsUterine Cervical NeoplasmsEarly Detection of CancerFemaleHumansMass ScreeningPapillomaviridaePolicyQuality ControlNucleic AcidsCervicalHPVPrimaryScreeningValidation

Identifiers

PMID36584621
PMCPMC11391586
OpenAlexW4313340131

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.