Evidence map›Paper›PMID 36584291›Full record

ArticleBiochemistry2023

Elucidating the Kinetic Mechanism of Human METTL16.

Kurtis Breger, Jessica A Brown

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Regulation of RNA-binding proteins by small biomolecules.Nature reviews. Molecular cell biology · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Structures and mechanisms of U6 snRNA mNature communications · 2025
    Article
  8. Article
  9. Article
  10. PRPS2 enhances RNA mNature communications · 2025
    Article
  11. Mechanisms and rationales of SAM homeostasis.Trends in biochemical sciences · 2025
    Review
  12. Methyl transfer in psilocybin biosynthesis.Nature communications · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Interconnections between mLife science alliance · 2024
    Review
  17. Ghost authors revealed: The structure and function of human NWiley interdisciplinary reviews. RNA · 2023
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kurtis BregerDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana46556, United States.ORCID 0000-0003-0066-4483
Jessica A BrownDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana46556, United States.ORCID 0000-0001-9055-5939
University of Notre Dame · US

Funding

Characterization of a Model System to Advance Triple-Stranded RNA BiologyR35GM133696 · NIGMS · UNIVERSITY OF NOTRE DAME · PI BROWN, JESSICA ANN · 2019 to 2023
$1.9M
Elucidating the Inhibitory Mechanisms of RNA Triple Helices in Nuclear DecayR00GM111430 · NIGMS · UNIVERSITY OF NOTRE DAME · PI BROWN, JESSICA ANN · 2016 to 2018
$743k
NIGMS NIH HHS R00 GM111430NIGMS NIH HHS R35 GM133696
6 · The paper itself

Abstract

Methyltransferase-like protein 16 (METTL16) is one of four catalytically active,

Indexed as

RNA, Long NoncodingHumansMethionine AdenosyltransferaseMethylationMethyltransferasesNucleic Acid ConformationRNA, MessengerRNA, Small NuclearRNA SplicingS-AdenosylmethionineMAT2A protein, humanMethionine AdenosyltransferaseMethyltransferasesMETTL16 protein, humanRNA, Long NoncodingRNA, MessengerRNA, Small NuclearS-Adenosylmethionine

Identifiers

PMID36584291
PMCPMC9850920
OpenAlexW4313340186

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.