Evidence map›Paper›PMID 36583204›Full record

ArticleClinical case reports2022

Dilemmas in the diagnosis and management of osteoporosis in a patient with alkaptonuria: Successful treatment with teriparatide.

Ismail C Ebrahim, Thanh D Hoang, Nicole O Vietor, John P Schacht, Mohamed K M Shakir

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Combined alkaptonuria and osteoporosis contributing to chronic back pain.Endocrinology, diabetes & metabolism case reports · 2025
    Article
  3. Alkaptonuria.Nature reviews. Disease primers · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ismail C EbrahimDivision of Endocrinology, Department of Medicine Walter Reed National Military Medical Center Bethesda Maryland USA.
Thanh D HoangDivision of Endocrinology, Department of Medicine Walter Reed National Military Medical Center Bethesda Maryland USA.ORCID https://orcid.org/0000-0001-7437-5604
Nicole O VietorDivision of Endocrinology, Department of Medicine Walter Reed National Military Medical Center Bethesda Maryland USA.
John P SchachtDepartment of Genetics Walter Reed National Military Medical Center Bethesda Maryland USA.
Mohamed K M ShakirDivision of Endocrinology, Department of Medicine Walter Reed National Military Medical Center Bethesda Maryland USA.ORCID https://orcid.org/0000-0001-5614-6402
Uniformed Services University of the Health Sciences · USWalter Reed National Military Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of osteoporosis in patients with alkaptonuria can be challenging. This is the first case report confirming the effectiveness of teriparatide following zoledronic acid therapy in treating osteoporosis and preventing fragility fractures in a patient with alkaptonuria.

Indexed as

alkaptonuriafracturesosteoporosisteriparatide

Identifiers

PMID36583204
PMCPMC9794677
OpenAlexW4313339592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.