Evidence map›Paper›PMID 36583160›Full record

ArticleTherapeutic advances in chronic disease2022

Chest X-ray features facilitate screening for pulmonary hypertension caused by fibrosing mediastinitis.

Mingfang Zhou, Bo Li, Yaling Chen, Aqian Wang, Yining Zhu, Yu Li, Hongling Su, Jingchun Fan, Yan Zhang, Yunshan Cao

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in chronic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Clinical Features and Survival in Fibrosing Mediastinitis: A Multicenter Cohort Study.Respiration; international review of thoracic diseases · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Mingfang ZhouThe First Clinical Medical College of Gansu University of Chinese Medicine (Gansu Provincial Hospital), Lanzhou, China.
Bo LiThe First Clinical Medical College of Gansu University of Chinese Medicine (Gansu Provincial Hospital), Lanzhou, China.ORCID https://orcid.org/0000-0002-5281-3295
Yaling ChenThe First Clinical Medical College of Gansu University of Chinese Medicine (Gansu Provincial Hospital), Lanzhou, China.
Aqian WangDepartment of Cardiology, Pulmonary Vascular Disease Center (PVDC), Gansu Provincial Hospital, Lanzhou, China.
Yining ZhuSchool of Mathematical Sciences, Fudan University, Shanghai, China.
Yu LiDepartment of Radiology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Hongling SuDepartment of Cardiology, Pulmonary Vascular Disease Center (PVDC), Gansu Provincial Hospital, Lanzhou, China.
Jingchun FanGansu University of Chinese Medicine, Lanzhou, China.
Yan ZhangTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, 251, Fukang Road, Nankai District, Tianjin, China.
Yunshan CaoDepartment of Cardiology, Pulmonary Vascular Disease Center (PVDC), Gansu Provincial Hospital, No. 204, Donggang West Road, Chengguan District, Lanzhou 730000, China.ORCID https://orcid.org/0000-0001-8463-1093
Gansu Provincial Hospital · CNFudan University · CNGansu University of Traditional Chinese Medicine · CNSun Yat-sen University · CNTianjin Medical University Eye Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Misdiagnosis and underdiagnosis of pulmonary hypertension caused by fibrosing mediastinitis (PH-FM) are considerably prevalent due to unspecific symptoms and as well as the lack of awareness of this fatal disease. Objectives: The aim of this study was to evaluate the diagnostic accuracy of the chest X-ray (CXR) for screening the patients with PH-FM from those with pulmonary hypertension (PH). Design: This was a retrospective observational cohort study. Methods: The patients with suspected PH were recruited between October 2014 and October 2020. All the clinical data and CXR findings were collected. The sensitivity, specificity, and likelihood ratio of the CXR features were calculated. Logistic regression was used to identify the factors associated with the CXR characteristics and FM and to generate a prediction model. Finally, the diagnostic efficiency of the prediction model was evaluated using nomogram and internal validation. Results: The patients with PH-FM ( Conclusion: In this study, atelectasis was the most specific and accurate CXR characteristic for identifying PH-FM in the PH patients. The combination of atelectasis, pleural effusion, prominent right heart border, tuberculosis, and lnBNP constituted a prediction model that distinguished the PH-FM patients from the PH-non-FM ones with good performance.

Indexed as

atelectasischest X-raydiagnosisfibrosing mediastinitispulmonary hypertensionright heart failure

Identifiers

PMID36583160
PMCPMC9793020
OpenAlexW4312824401

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.