Evidence map›Paper›PMID 36583135›Full record

ArticleToxicology reports2023

Anticancer potential of phytochemicals from

Sheikh Sunzid Ahmed, M Oliur Rahman, Ali S Alqahtani, Nahid Sultana, Omer M Almarfadi, M Ajmal Ali, Joongku Lee

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Sheikh Sunzid AhmedDepartment of Botany, University of Dhaka, Dhaka 1000, Bangladesh.
M Oliur RahmanDepartment of Botany, University of Dhaka, Dhaka 1000, Bangladesh.
Ali S AlqahtaniDepartment of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Nahid SultanaDepartment of Botany, Jagannath University, Dhaka 1100, Bangladesh.
Omer M AlmarfadiDepartment of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
M Ajmal AliDeperment of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Joongku LeeDepartment of Environment and Forest Resources, Chungnam National University, Daehak-ro, Yuseong-gu, Daejeon, Republic of Korea.
King Saud University · SAUniversity of Dhaka · BDChungnam National University · KRJagannath University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, small molecule inhibition of LDHA (Lactate Dehydrogenase A) has evolved as an appealing option for anticancer therapy. LDHA catalyzes the interconversion of pyruvate and lactate in the glycolysis pathway to play a crucial role in aerobic glycolysis. Therefore, in the current investigation LDHA was targeted with bioactive phytochemicals of an ethnomedicinally important plant species

Indexed as

CancerLactate Dehydrogenase AMM/GBSAMolecular dockingMolecular dynamics simulationOroxylum indicum

Identifiers

PMID36583135
PMCPMC9792705
OpenAlexW4313340252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.