Evidence map›Paper›PMID 36583093›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2022

Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome.

Robert E Morris, Ferenc Kuhn, Timothy Sipos

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07146516 (Ora Secunda Cerclage Laser Retinopexy To Prevent Retinal Detachment In Stickler Syndrome), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07146516 narecruitingnot on this mapstarted 2025, after this paper: background citation

Ora Secunda Cerclage Laser Retinopexy To Prevent Retinal Detachment In Stickler Syndrome (OSC/SS): A Prospective Historically Controlled Study

TypeinterventionalSponsorHelen Keller Eye Research FoundationRan2025 to 2035Enrolled500ConditionsStickler Syndrome Type 1, Stickler Syndrome Type 2ArmsProphylactic (non-invasive) Laser Retinopexy
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Correspondence.Retina (Philadelphia, Pa.) · 2025
    Article
  5. Article
  6. Article
  7. Vitrectomy as a Prevention for Retinal Detachment in High-Risk Eyes.Clinical ophthalmology (Auckland, N.Z.) · 2025
    Article
  8. Article
  9. Rhegmatogenous retinal detachment: time to consider real prevention.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Robert E MorrisRetina Specialists of Alabama, LLC, Birmingham, AL, USA.ORCID 0000-0003-4762-4817
Ferenc KuhnHelen Keller Foundation for Research and Education, Birmingham, AL, USA.
Timothy SiposRetina Specialists of Alabama, LLC, Birmingham, AL, USA.
University of Alabama at Birmingham · USHelen Keller Eye Research Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stickler syndrome, a rare inherited disease, carries a lifetime risk of rhegmatogenous retinal detachment (RRD) of up to 65%, higher than any other predisposing condition known. Both syndromic and non-syndromic eyes suffer RRD predominately from the same pathogenesis, vitreous tractional tears in the peripheral retina. Consequently, extraordinary publications in 2021-2022, each reporting successful prevention of RRD in Stickler syndrome, using 360-degree (encircling) laser retinopexy, provide the first strong evidence upon which similar prophylaxis in non-syndromic eyes at high risk of RRD from peripheral retinal tears can confidently go forward.

Indexed as

360-degree laser retinopexyencircling laser prophylaxisretinal detachmentretinal detachment preventionretinal tearstickler syndrome

Identifiers

PMID36583093
PMCPMC9793794
OpenAlexW4312188906

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.