ArticleFrontiers in endocrinology2022
The concentrations of bone calcium, phosphorus and trace metal elements in elderly patients with intertrochanteric hip fractures.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 8 citations in OpenAlex.
- Correlation of serum vitamin D, calcium-phosphorus metabolism and functional outcome in osteoporotic fractures.Bioinformation · 2026Article
- Serum iron levels as a risk factor for Osteoporosis-Related pathological fractures.Aging clinical and experimental research · 2025Article
- Article
- Diversity of the diet is correlated with osteoporosis in post-menopausal women: an Iranian case-control study.Frontiers in public health · 2024Article
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5 authors at 1 institution in 1 country.
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Abstract
Introduction: Trace metal elements may play a crucial role in bone mineralization and metabolism. However, the quantification of trace element concentrations in human bone tissue has received little attention. Materials and methods: Bone tissue samples were collected from 55 elderly patients (15 males and 40 females) with intertrochanteric hip fractures. The calcium, phosphorus, manganese, iron, copper, and zinc concentrations in the cortical bone zone, cancellous bone zone, and junction zone between cortical and cancellous bone were determined by energy-dispersive X-ray fluorescence (EDX). The differences in trace element concentrations in the three regions were compared, and the correlation between gender and bone trace element contents of the bones was analyzed using the Kruskal-Wallis's test. The correlation between age, body mass index (BMI), and bone calcium, phosphorus concentrations, and trace elements in three bone zones was determined using Spearman correlation analysis. Results: The Kruskal-Wallis test showed no difference in bone phosphorus concentration among the three regions. In contrast, the difference in the concentrations of bone calcium and four metal elements was statistically significant ( Conclusion: Bone calcium and phosphorus were the main components of hydroxyapatite, and these two elements accounted for the majority of bone mineral salts. Trace metal elements are essential for bone metabolism and specific synergistic interactions. BMI may be associated with bone calcium and phosphorus contents in elderly patients with osteoporosis.
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