A case report of transcatheter repair of severe functional mitral regurgitation in cardiac amyloidosis.

Meng Fangmin, Lu Shaohua, Wei Lai, Pan Cuizhen

Open access · goldAbstract readCase Reports

In one paragraph

Article in European heart journal. Case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 87% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

Successful Transcatheter Mitral Valve Repair for Iatrogenic Chordal Rupture in Cardiac Amyloidosis.JACC. Case reports · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Meng FangminShanghai Institute of Medical Imaging, Fudan University, 180 Fenglin Road, 200032 Shanghai, China.ORCID https://orcid.org/0000-0001-5794-1563

Lu ShaohuaDepartment of pathology, Zhongshan Hospital, Fudan University, 180 Fenglin Road, 200032 Shanghai, China.

Wei LaiDepartment of Cardiac Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, 200032 Shanghai, China.

Pan CuizhenShanghai Institute of Medical Imaging, Fudan University, 180 Fenglin Road, 200032 Shanghai, China.ORCID https://orcid.org/0000-0001-7697-9970

Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcatheter therapy has become an alternative for functional mitral regurgitation (FMR) in patients at high surgical risk. However, the intervention of FMR in cardiac amyloidosis (CA) with transcatheter edge-to-edge repair (TEER) is controversial due to the potential risk of left atrial pressure (LAP) elevation. Case summary: An 83-year-old woman with repeated heart failure (HF) and severe mitral regurgitation (MR) was referred to our centre for TEER. Pre-procedural transthoracic echocardiography (TTE) and transoesophageal echocardiography (TOE) confirmed the degree of MR and a functional aetiology. A peculiar LAP increase in this patient occurred immediately after successful TEER clip implantation and her Discussion: Severe functional MR in CA treated with TEER has the potential risk of increasing LAP. During the short-term follow-up, TEER appears beneficial for left heart function (reduction of MR) but harmful for right heart function (increase of LAP). CA patients with severe FMR should be carefully evaluated about the benefits and potential harm of TEER intervention.

Indexed as

Cardiac amyloidosisCase reportMitral regurgitationTranscatheter edge-to-edge repair

Identifiers

PMID36582592

DOI10.1093/ehjcr/ytac471

PMCPMC9792274

OpenAlexW4311953973

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LicenceCC BY-NC

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.