Evidence map›Paper›PMID 36582567›Full record

ArticleCureus2022

Disparities in Postoperative Endocrine Outcomes After Endoscopic-Assisted Transsphenoidal Pituitary Adenoma Resection.

Chhitij Tiwari, Eugene Maung, Aaron Gelinne, Nathan Quig, Brian Thorp, Adam Zanation, Matthew Ewend, Deanna Sasaki-Adams, Carolyn Quinsey

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chhitij TiwariDepartment of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Eugene MaungDepartment of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Aaron GelinneDepartment of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Nathan QuigDepartment of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Brian ThorpDepartment of Otolaryngology - Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Adam ZanationDepartment of Otolaryngology - Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Matthew EwendDepartment of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Deanna Sasaki-AdamsDepartment of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Carolyn QuinseyDepartment of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Carolina Ear, Nose and Throat Clinic · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives Socioeconomic factors can influence morbidity in patients with pituitary adenoma. This study aims to identify associations between socioeconomic factors and postoperative outcomes in patients with pituitary adenomas. Methods A retrospective medical chart review was conducted on adult patients who underwent resection of purely sellar nonfunctional and functional pituitary adenomas between May 1, 2014, and May 31, 2020, at the University of North Carolina Medical Center. The main outcome measures included the incidence of postoperative diabetes insipidus (PDI), postoperative hyponatremia (PHN), and postoperative hypopituitarism (PHP). Outcome measures were analyzed using univariate and multivariate analyses against preoperative tumor volume as well as socioeconomic and demographic factors (self-identified race/ethnicity, age, gender, address assessed by the Area Deprivation Index (ADI), and insurance status). Results On univariate analysis, patients of Hispanic race/ethnicity and patients living in more disadvantaged neighborhoods had an increased incidence of postoperative diabetes insipidus. Patients who experienced PDI were significantly younger on average in both univariate and multivariate analyses. When analyzed further, patients of Hispanic race/ethnicity were significantly younger and more likely to be uninsured compared to their respective racial/ethnic counterparts. No significant correlations were found for PHN or PHP. Conclusions Patients of Hispanic race/ethnicity and patients living in more disadvantaged neighborhoods were more likely to experience PDI. This finding, when combined with findings regarding age and insurance status, suggests complex disparities in medical care that are confirmed or corroborated by prior literature. These results may enhance clinicians' management of patients from disadvantaged socioeconomic backgrounds through increased awareness of disparities and the provision of resources for assistance.

Indexed as

diabetes insipidusendoscopic sinus surgerypituitary adenomaskull basesocioeconomic disparities

Identifiers

PMID36582567
PMCPMC9794913
OpenAlexW4310268116

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.