Evidence map›Paper›PMID 36582392›Full record

ArticleBioinformatics and biology insights2022

Molecular Modeling Targeting the ACE2 Receptor with

Zainab El Ouafi, Wajih Rhalem, Nihal Habib, Abdellah Idrissi Azami, Sofia Sehli, Najib Al Idrissi, Fadil Bakkali, Rfaki Abderrazak, Mohamed Merzouki, Imane Allali and 3 more

Open access · goldAbstract read
In one paragraph

Article in Bioinformatics and biology insights, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Antiviral activities of hemp cannabinoids.Clinical science (London, England : 1979) · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Zainab El OuafiLaboratory of Genomics and Bioinformatics, School of Pharmacy, Mohammed VI University of Health Sciences Casablanca, Casablanca, Morocco.
Wajih RhalemElectronic Systems, Sensors and Nanobiotechnologies (E2SN), École Nationale Supérieure des Arts et Métiers (ENSAM), Mohammed V University, Rabat, Morocco.
Nihal HabibLaboratory of Genomics and Bioinformatics, School of Pharmacy, Mohammed VI University of Health Sciences Casablanca, Casablanca, Morocco.
Abdellah Idrissi AzamiLaboratory of Genomics and Bioinformatics, School of Pharmacy, Mohammed VI University of Health Sciences Casablanca, Casablanca, Morocco.
Sofia SehliLaboratory of Genomics and Bioinformatics, School of Pharmacy, Mohammed VI University of Health Sciences Casablanca, Casablanca, Morocco.
Najib Al IdrissiDepartment of Surgery, School of Medicine, Mohammed VI University of Health Sciences Casablanca, Casablanca, Morocco.
Fadil BakkaliToxicology Laboratory, School of Medicine, Mohammed VI University of Health Sciences (UM6SS) Casablanca, Casablanca, Morocco.
Rfaki AbderrazakNational Center for Scientific and Technical Research (CNRST), Rabat, Morocco.
Mohamed MerzoukiBioengineering Laboratory, Faculty of Science and Technologies, University of Sultan Moulay Slimane, Beni Mellal, Morocco.
Imane AllaliLaboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco.
Saaïd AmzaziLaboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco.
Chakib NejjariDepartment of Epidemiology and Biostatistics, International School of Public Health, Mohammed VI University of Health Sciences Casablanca, Casablanca, Morocco.
Hassan GhazalLaboratory of Genomics and Bioinformatics, School of Pharmacy, Mohammed VI University of Health Sciences Casablanca, Casablanca, Morocco.
Université Mohammed VI des Sciences de la Santé · MAMohammed V University · MANational Centre for Nuclear Energy, Science and Technology · MAUniversité Sultan Moulay Slimane · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of a novel coronavirus that later on rendered a global pandemic, caused desperation within the communities and drove increased interest in exploring medicinal plant-based therapeutics to treat and prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infections. Many medicinal plants have been reported to have antiviral, anti-inflammatory, and immunomodulatory effects that hinder, cure, or ease the symptoms of COVID-19 infection. This exploratory study seeks to dock the active components of

Indexed as

ACE2ADMETCannabis sativaCOVID-19drug discoveryMedicinal plantmolecular dockingSARS-CoV-2spike

Identifiers

PMID36582392
PMCPMC9793058
OpenAlexW4312850775

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.