Evidence map›Paper›PMID 36582351›Full record

ArticleBioactive materials2023

Smart dental materials for antimicrobial applications.

Carolina Montoya, Lina Roldan, Michelle Yu, Sara Valliani, Christina Ta, Maobin Yang, Santiago Orrego

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolina MontoyaDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA.
Lina RoldanDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA.
Michelle YuDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA.
Sara VallianiDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA.
Christina TaDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA.
Maobin YangDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA.
Santiago OrregoDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA.

Funding

Effect of piezoelectric charges on oral microbiome modulationR21DE030564 · NIDCR · TEMPLE UNIV OF THE COMMONWEALTH · PI ORREGO, SANTIAGO · 2021 to 2022
$457k
Synergistic degradation of the bonded interface: A new approach to evaluate the bond strength of dental restorationR03DE030562 · NIDCR · TEMPLE UNIV OF THE COMMONWEALTH · PI MELO, MARY ANNE SAMPAIO DE, ORREGO, SANTIAGO · 2022 to 2023
$330k
NIDCR NIH HHS R03 DE030562NIDCR NIH HHS R21 DE030564
6 · The paper itself

Abstract

Smart biomaterials can sense and react to physiological or external environmental stimuli (e.g., mechanical, chemical, electrical, or magnetic signals). The last decades have seen exponential growth in the use and development of smart dental biomaterials for antimicrobial applications in dentistry. These biomaterial systems offer improved efficacy and controllable bio-functionalities to prevent infections and extend the longevity of dental devices. This review article presents the current state-of-the-art of design, evaluation, advantages, and limitations of bioactive and stimuli-responsive and autonomous dental materials for antimicrobial applications. First, the importance and classification of smart biomaterials are discussed. Second, the categories of bioresponsive antibacterial dental materials are systematically itemized based on different stimuli, including pH, enzymes, light, magnetic field, and vibrations. For each category, their antimicrobial mechanism, applications, and examples are discussed. Finally, we examined the limitations and obstacles required to develop clinically relevant applications of these appealing technologies.

Indexed as

AntibacterialAntibiofilmAntifungalAntimicrobialBioactiveBiofilmBioresponsive biomaterialsRestorative dentistrySmart dental materialsStimuli-responsive

Identifiers

PMID36582351
PMCPMC9763696

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.