Evidence map›Paper›PMID 36581933›Full record

ArticleInternational journal for equity in health2022

Catastrophic pharmaceutical expenditure in patients with type 2 diabetes in Iran.

Leila Zarei, Najmeh Moradi, Farzad Peiravian, Nazafarin Hatami-Mazinani, Motahareh Mahi-Birjand, Jalal Arabloo, Zaheer-Ud-Din Babar

Open access · goldAbstract read
In one paragraph

Article in International journal for equity in health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Leila ZareiAssistant Professor in Pharmacoeconomics and Pharma Management, Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Fars, Iran.ORCID 0000-0002-4459-8599
Najmeh MoradiAssistant Professor in Pharmacoeconomics and Pharmaceutical Management, Health Management and Economics Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran. najme.moradi@gmail.com.
Farzad PeiravianAssistant Professor in Pharmacoeconomics and Pharma Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nazafarin Hatami-MazinaniDepartment of Clinical Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Motahareh Mahi-BirjandDepartment of Clinical Pharmacy, School of Pharmacy, Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Jalal ArablooAssistant Professor in Health Policy Making, Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.
Zaheer-Ud-Din BabarProfessor in Medicines and Healthcare. Department of Pharmacy, University of Huddersfield, Queensgate, HD1 3DH, Huddersfield, UK.
Iran University of Medical Sciences · IRShiraz University of Medical Sciences · IRBirjand University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRUniversity of Huddersfield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to assess the financial burden of out-of-pocket (OOP) payments to purchase antidiabetic medicines for type 2 patients in Iran.

methodThe "budget share" and "capacity to pay" approaches were employed to assess the catastrophic pharmaceutical expenditures of antidiabetic medication therapies. The catastrophic thresholds were adjusted for pharmaceutical sectors. The data was 2019 monthly household expenditures in rural and urban areas, insurance coverages of antidiabetic medicines and patients' out-of-pocket (OOP) payments in 30-day treatment schedules.

resultsThe results show that expenditure on diabetes medication therapies in the form of mono-dual therapy and some cases triple oral therapies were not catastrophic even for rural households. Insulin puts patients at risk of catastrophic pharmaceutical expenditures when added to the treatment schedules, and lack of financial protection intensifies it. In general, the poorer households and those resistant to first-line treatments were at increased risk of catastrophic pharmaceutical expenditures. The number of treatments that put patients at risk of catastrophic pharmaceutical expenditure in "budget share" was higher than the "capacity to pay" approach.

conclusionsAssessing medication treatment affordability instead of a single medicine assessment is needed. Assessment could be done by utilizing a macro-level data approach and applying adjusted pharmaceutical sector threshold values. Considering the variation between treatment schedules that put patients at risk of catastrophic pharmaceutical expenditures, targeted pharmaceutical policies and reimbursement decisions are recommended to promote Universal Health Coverage (UHC) and to protect vulnerable populations from hardship.

Indexed as

Diabetes Mellitus, Type 2Health ExpendituresCatastrophic IllnessHumansHypoglycemic AgentsIranPharmaceutical PreparationsPovertyHypoglycemic AgentsPharmaceutical PreparationsCatastrophic expendituresDiabetesMedicationMiddle-income countriesOut of pocket

Identifiers

PMID36581933
PMCPMC9798561
OpenAlexW4313331487

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.