Evidence map›Paper›PMID 36581812›Full record

ArticleBMC pulmonary medicine2022

Change in health outcomes for First Nations children with chronic wet cough: rationale and study protocol for a multi-centre implementation science study.

Pamela J Laird, Roz Walker, Gabrielle McCallum, Maree Toombs, Melanie Barwick, Peter Morris, Robyn Aitken, Matthew Cooper, Richard Norman, Bhavini Patel and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Pamela J LairdWal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, WA, Australia.
Roz WalkerSchool of Indigenous Studies, Poche Centre for Indigenous Health, University of Western Australia, Perth, WA, Australia.
Gabrielle McCallumChild Health Division Menzies School of Health Research, Charles Darwin University, NT, Darwin, Australia.
Maree ToombsFaculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
Melanie BarwickHospital for Sick Children, Toronto, Canada.
Peter MorrisChild Health Division Menzies School of Health Research, Charles Darwin University, NT, Darwin, Australia.
Robyn AitkenChild Health Division Menzies School of Health Research, Charles Darwin University, NT, Darwin, Australia.
Matthew CooperWal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, WA, Australia.
Richard NormanSchool of Population Health, Curtin University, Perth, WA, Australia.
Bhavini PatelNorthern Territory Department of Health, Darwin, NT, Australia.
Gloria LauWal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, WA, Australia.
Anne B ChangChild Health Division Menzies School of Health Research, Charles Darwin University, NT, Darwin, Australia.
André SchultzWal-yan Respiratory Research Centre, Telethon Kids Institute, Perth, WA, Australia. Andre.Schultz@health.wa.gov.au.ORCID http://orcid.org/0000-0002-2000-8910
The Kids Research Institute Australia · AUCharles Darwin University · AUCurtin University · AUFlinders University · AUMurdoch University · AUNorthern Territory Health Services · AUQueensland University of Technology · AUThe University of Queensland · AUUniversity of Toronto · CA

Funding

National Health and Medical Research Council APP1170735
6 · The paper itself

Abstract

backgroundIn children, chronic wet cough may be a sign of underlying lung disease, including protracted bacterial bronchitis (PBB) and bronchiectasis. Chronic (> 4 weeks in duration) wet cough (without indicators pointing to alternative causes) that responds to antibiotic treatment is diagnostic of PBB. Timely recognition and management of PBB can prevent disease progression to irreversible bronchiectasis with lifelong consequences. However, detection and management require timely health-seeking by carers and effective management by clinicians. We aim to improve (a) carer health-seeking for chronic wet cough in their child and (b) management of chronic wet cough in children by clinicians. We hypothesise that implementing a culturally integrated program, which is informed by barriers and facilitators identified by carers and health practitioners, will result in improved lung health of First Nations children, and in the future, a reduced the burden of bronchiectasis through the prevention of the progression of protracted bacterial bronchitis to bronchiectasis.

methodsThis study is a multi-centre, pseudorandomised, stepped wedge design. The intervention is the implementation of a program. The program has two components: a knowledge dissemination component and an implementation component. The implementation is adapted to each study site using a combined Aboriginal Participatory Action Research and an Implementation Science approach, guided by the Consolidated Framework of Implementation Research. There are three categories of outcome measures related to (i) health (ii) cost, and (iii) implementation. We will measure health-seeking as the proportion of parents seeking help for their child in a 6-month period before the intervention and the same 6-month period (i.e., the same six calendar months) thereafter. The parent-proxy, Cough-specific Quality of Life (PC-QoL) will be the primary health-related outcome measure. DISCUSSION: We hypothesise that a tailored intervention at each site will result in improved health-seeking for carers of children with a chronic wet cough and improved clinician management of chronic wet cough. In addition, we expect this will result in improved lung health outcomes for children with a chronic wet cough.

trial registrationAustralian New Zealand Clinical Trials Registry; ACTRN12622000430730 , registered 16 March 2022, Retrospectively registered.

Indexed as

Bacterial InfectionsBronchiectasisBronchitisBronchitis, ChronicAustraliaChildChronic DiseaseCoughHumansImplementation ScienceMulticenter Studies as TopicOutcome Assessment, Health CareQuality of LifeChronic wet coughFirst Nations childrenKnowledge TranslationProtracted bacterial bronchitis

Identifiers

PMID36581812
PMCPMC9798941
OpenAlexW4313331552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.