ArticleScientific data2022
A transcriptome dataset for gonadectomy-induced changes in rat spinal cord.
Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Sexual dimorphisms in phrenic long-term facilitation following severe acute intermittent hypoxia.Journal of neurophysiology · 2026Article
- Daily acute intermittent hypoxia elicits age & sex-dependent changes in molecules regulating phrenic motor plasticity.Experimental neurology · 2025Article
- Age and estrogen-associated reductions in hypoxic ventilatory response and chemosensitivity in female rats.Frontiers in physiology · 2024Article
- Article
- A transcriptome dataset for gonadectomy-induced changes in rat spinal cord.Scientific data · 2022Article
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Authors and funding
4 authors at 3 institutions in 1 country.
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Abstract
Circulating sex steroid hormones are critical for neural function and development of neuroplasticity in many regions of the central nervous system. In the spinal cord, our knowledge of steroid hormone influence mostly derives from mechanistic studies of pain processing in dorsal spinal cord circuits; less is known regarding hormonal influence of ventral spinal motor function. Gonadectomy (surgical removal of the testes in males and ovaries in females) rapidly and persistently reduces circulating sex steroids in both females and males, providing a means to interrogate the role of hormones on neural function. Here we provide a next-generation RNA sequencing (RNA-seq) data set to evaluate the impact of gonadectomy on the transcriptome of ventral spinal cord tissue of adult female and male rats.
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