ArticleThe Korean journal of pain2023
Primary somatosensory cortex and periaqueductal gray functional connectivity as a marker of the dysfunction of the descending pain modulatory system in fibromyalgia.
Article in The Korean journal of pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 13 citations in OpenAlex.
- Trial
- Dynamic reconfiguration of directed effective connectivity between attention networks and the default mode network in knee osteoarthritis: a combined resting-state and non-noxious thermal stimulation functional magnetic resonance imaging study.The Korean journal of pain · 2026Article
- Pain Mechanisms in Fibromyalgia: An Integrative Narrative Review of Central, Peripheral, Neuroimmune, and Psychobiological Factors.Biomedicines · 2026Review
- New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study.Arthritis care & research · 2026Article
- Concordance of cortical morphological anomalies with genetic predisposition to multisite chronic pain in females.The Korean journal of pain · 2026Article
- Linalyl acetate alleviates inflammatory pain via OLFR482 activation in the mouse anterior cingulate cortex.Frontiers in pharmacology · 2026Article
- Functional connectivity of the periaqueductal grey subdivisions is disrupted in chronic low back pain.Brain imaging and behavior · 2025Article
- Major depressive disorder in fibromyalgia: novel insights from resting-state functional connectivity analysis.The Korean journal of pain · 2025Article
- Differential brainstem connectivity according to sex and menopausal status in healthy male and female individuals.Biology of sex differences · 2025Article
- Biochemical strategies for opioid-sparing pain management in the operating room.Biochemistry and biophysics reports · 2025Review
- Fibromyalgia: A Review of the Pathophysiological Mechanisms and Multidisciplinary Treatment Strategies.Biomedicines · 2024Review
- Repetitive Transcranial Magnetic Stimulation in Fibromyalgia: Exploring the Necessity of Neuronavigation for Targeting New Brain Regions.Journal of personalized medicine · 2024Review
- Psycho-Neuroendocrinology in the Rehabilitation Field: Focus on the Complex Interplay between Stress and Pain.Medicina (Kaunas, Lithuania) · 2024Review
- Disrupted Sensorimotor Network Integration in Women With Fibromyalgia Revealed by Resting-State Functional MRI.Journal of neuroimaging : official journal of the American Society of NeuroimagingArticle
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Resting-state functional connectivity (rs-FC) may aid in understanding the link between pain-modulating brain regions and the descending pain modulatory system (DPMS) in fibromyalgia (FM). This study investigated whether the differences in rs-FC of the primary somatosensory cortex in responders and non-responders to the conditioned pain modulation test (CPM-test) are related to pain, sleep quality, central sensitization, and the impact of FM on quality of life. Methods: This cross-sectional study included 33 females with FM. rs-FC was assessed by functional magnetic resonance imaging. Change in the numerical pain scale during the CPM-test assessed the DPMS function. Subjects were classified either as non-responders ( Results: Non-responders showed a decreased rs-FC between the left somatosensory cortex (S1) and the periaqueductal gray (PAG) ( Conclusions: These results support using the rs-FC patterns in the left S1-PAG as a marker for predicting CPM-test response, which may aid in treatment individualization in FM patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.