Evidence map›Paper›PMID 36581456›Full record

ArticleAJNR. American journal of neuroradiology2023

Dilated Optic Nerve Sheath in Mucopolysaccharidosis I: Common and Not Necessarily High Intracranial Pressure.

S Huang, T Lund, P Orchard, A Gupta, D Nascene

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

S HuangFrom the Department of Neurosurgery (S.H.) huan2256@umn.edu.ORCID 0000-0003-4366-3309
T LundDivision of Pediatric Blood and Marrow Transplant (T.L., P.O., A.G.).ORCID 0000-0001-9174-8919
P OrchardDivision of Pediatric Blood and Marrow Transplant (T.L., P.O., A.G.).ORCID 0000-0001-9426-1292
A GuptaDivision of Pediatric Blood and Marrow Transplant (T.L., P.O., A.G.).ORCID 0000-0001-5679-5533
D NasceneDepartment of Radiology (D.N.), University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-2468-7359
NHS Blood and Transplant · GBHuaian First People’s Hospital · CNUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrocephalus is one of the earliest manifestations of mucopolysaccharidosis I-Hurler syndrome, and delayed treatment of hydrocephalus can lead to neurocognitive delay or even death. Optic nerve sheath diameter has been established as a noninvasive measurement to detect elevated intracranial pressure. This study aimed to establish correlations between optic nerve sheath diameter and opening pressure. Forty-nine MR images and opening pressures in patients with mucopolysaccharidosis I-Hurler syndrome were retrospectively reviewed from 2008 to 2020. The optic nerve sheath diameter was measured 3 mm posterior to the posterior margin of the globe (retrobulbar) and 10 mm anterior to the optic foramen (midpoint segment), and the average was taken between the 2 eyes. Opening pressure was measured with the patient in the lateral decubitus position with controlled end-tidal CO

Indexed as

HydrocephalusIntracranial HypertensionMucopolysaccharidosis IHumansIntracranial PressureOptic NerveRetrospective StudiesUltrasonography

Identifiers

PMID36581456
PMCPMC9835902
OpenAlexW4313272288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.