Evidence map›Paper›PMID 36581426›Full record

ArticleBMJ open2022

Prevalence of prediabetes and associated factors of prediabetic stages: a cross-sectional study among adults in Nepal.

Pushpanjali Shakya, Archana Shrestha, Biraj Man Karmacharya, Abha Shrestha, Bård Eirik Kulseng, Eva Skovlund, Abhijit Sen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04074148 (Effectiveness of Diabetes Prevention Education Program on Diabetes Prevention Among Prediabetes Population in Nepal), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04074148 nacompletednot on this map

Effectiveness of Diabetes Prevention Education Program on Diabetes Prevention Among Prediabetes Population in Nepal: A Cluster Randomized Controlled Trial

TypeinterventionalSponsorNorwegian University of Science and TechnologyRan2019 to 2021Enrolled291ConditionsPrediabetic StateArmsDiabetes Prevention Education Program, Diabetes Prevention Education brochure
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Pushpanjali ShakyaDepartment of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway pushpanjalishakyabajra@gmail.com.ORCID 0000-0002-1073-4812
Archana ShresthaDepartment of Public Health and Community Programs, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.ORCID 0000-0002-4741-090X
Biraj Man KarmacharyaDepartment of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0001-8983-0235
Abha ShresthaDepartment of Community Medicine, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.ORCID 0000-0002-7992-7137
Bård Eirik KulsengDepartment of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0002-7672-2312
Eva SkovlundDepartment of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0002-2997-6141
Abhijit SenDepartment of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0001-9560-4226
Norwegian University of Science and Technology · NOYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate the prevalence of prediabetes and to assess the association of prediabetic stages with sociodemographic, lifestyle and clinical factors

designCross-sectional study at the screening and inclusion stage of a Diabetes Prevention Education Program (DiPEP) trial

settingThe study was conducted in two urban communities in Nepal (October 2019-March 2020).

participantsA total of 6222 residents of two study sites, aged 18-64 years and without a history of diabetes, were eligible for prediabetes screening. Exclusion criteria were pregnancy, history of diabetes and critical illness. A total of 291 participants with prediabetes were included in this study. PRIMARY AND SECONDARY OUTCOME MEASURES: Prevalence of prediabetes based on glycated haemoglobin (HbA1c) criteria (5.7%-6.4%) was the primary outcome of the study. Odds Ratio and 95% CI were estimated to assess the associations between the outcome prediabetic stages (5.7%-5.9% vs 6.0%-6.4%) and sociodemographic, lifestyle and clinical factors in both unadjusted and adjusted models.

resultsOut of 6222 screened participants, 308 (5%, 95% CI: 4.4% to 5.5%) individuals were detected with prediabetes based on HbA1c. The mean age of 291 responded participants was 50.3±7.6 years and 67% were females. Among them, 78% aged 45-64 years, 97% had central obesity, 90% had high waist-hip ratio, 63% were hypertensive and 66% had no family history of diabetes. Approximately, 54% and 46% of individuals with prediabetes had HbA1c of 5.7%-5.9% and 6.0%-6.4%, respectively. Female gender was associated with prediabetes with HbA1c 6.0%-6.4% (OR, 1.98, 95% CI: 1.07 to 3.67) in the adjusted model.

conclusionThe estimated prevalence of prediabetes was 5% among screened participants, and female gender was associated with the prediabetic stage. As a large proportion of the population with prediabetes were not aware of their status, this study demonstrates a need for regular community screening programmes to detect individuals with prediabetes and provide them a comprehensive lifestyle intervention for diabetes prevention. TRIAL REGISTRATION NUMBER: NCT04074148, 2019/783.

Indexed as

Diabetes MellitusPrediabetic StateAdultBlood GlucoseCross-Sectional StudiesFemaleGlycated HemoglobinHumansMaleNepalPrevalenceRisk FactorsBlood GlucoseGlycated HemoglobinGeneral diabetesPREVENTIVE MEDICINEPUBLIC HEALTH

Identifiers

PMID36581426
PMCPMC9806022
OpenAlexW4313271305

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.