Evidence map›Paper›PMID 36581411›Full record

ArticleBMJ open2022

Treatment decision-making and care among older adults with kidney failure: protocol for a multicentre, prospective observational cohort study with nested substudies and linked qualitative research (the Elderly Advanced CKD Programme).

Amanda Siriwardana, Nicholas A Gray, Angela Makris, Chenlei Kelly Li, Kenneth Yong, Yachna Mehta, Jannel Ramos, Gian Luca Di Tanna, Chris Gianacas, Isaac Yeboah Addo and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Amanda SiriwardanaRenal and Metabolic Division, The George Institute for Global Health, Sydney, New South Wales, Australia asir3810@uni.sydney.edu.au.ORCID 0000-0003-2417-8500
Nicholas A GrayDepartment of Renal Medicine, Sunshine Coast Hospital and Health Service, Birtinya, Queensland, Australia.ORCID 0000-0001-9112-0304
Angela MakrisDepartment of Renal Medicine, Liverpool Hospital, Sydney, New South Wales, Australia.
Chenlei Kelly LiDepartment of Renal Medicine, St George Hospital, Sydney, New South Wales, Australia.
Kenneth YongDepartment of Renal Medicine, Prince of Wales Hospital and Community Health Services, Sydney, New South Wales, Australia.
Yachna MehtaRenal and Metabolic Division, The George Institute for Global Health, Sydney, New South Wales, Australia.
Jannel RamosRenal and Metabolic Division, The George Institute for Global Health, Sydney, New South Wales, Australia.
Gian Luca Di TannaStatistics Division, George Institute for Global Health, Sydney, New South Wales, Australia.
Chris GianacasStatistics Division, George Institute for Global Health, Sydney, New South Wales, Australia.
Isaac Yeboah AddoFaculty of Arts and Social Sciences, University of New South Wales Centre for Social Research in Health, Sydney, New South Wales, Australia.
Sarah RoxburghSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Vasi NaganathanSydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0001-7243-0796
Celine FooteDepartment of Renal Medicine, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Martin GallagherRenal and Metabolic Division, The George Institute for Global Health, Sydney, New South Wales, Australia.
The George Institute for Global Health · AUThe University of Sydney · AULiverpool Hospital · AUUNSW Sydney · AUConcord Repatriation General Hospital · AUSt George Hospital · AUUniversity of the Sunshine Coast · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionShared treatment decision-making and planning of care are fundamental in advanced chronic kidney disease (CKD) management. There are limited data on several key outcomes for the elderly population including survival, quality of life, symptom burden, changes in physical functioning and experienced burden of healthcare. Patients, caregivers and clinicians consequently face significant uncertainty when making life-impacting treatment decisions. The Elderly Advanced CKD Programme includes quantitative and qualitative studies to better address challenges in treatment decision-making and planning of care among this increasingly prevalent elderly cohort. METHODS AND ANALYSIS: The primary component is OUTcomes of Older patients with Kidney failure (OUTLOOK), a multicentre prospective observational cohort study that will enrol 800 patients ≥75 years with kidney failure (estimated glomerular filtration rate ≤15 mL/min/1.73 m ETHICS AND DISSEMINATION: Ethics approval was obtained through Sydney Local Health District Human Research Ethics Committee (2019/ETH07718, 2020/ETH02226, 2021/ETH01020, 2019/ETH07783). OUTLOOK is approved to have waiver of individual patient consent. TIMELY, Co-TIMELY and CONTEND participants will provide written informed consent. Final results will be disseminated through peer-reviewed journals and presented at scientific meetings.

Indexed as

Kidney Failure, ChronicRenal Insufficiency, ChronicAgedHumansMulticenter Studies as TopicObservational Studies as TopicProspective StudiesQualitative ResearchQuality of LifeRenal DialysisEnd stage renal failureGERIATRIC MEDICINESTATISTICS & RESEARCH METHODS

Identifiers

PMID36581411
PMCPMC9806093
OpenAlexW4313271224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.