Evidence map›Paper›PMID 36581193›Full record

ArticleAmerican journal of ophthalmology2023

Vision-Related Quality of Life Among Healthy, Preperimetric Glaucoma, and Perimetric Glaucoma Patients.

Takashi Nishida, Sasan Moghimi, Maya L M Yamane, Jo-Hsuan Wu, Vahid Mohammadzadeh, Alireza Kamalipour, Golnoush Mahmoudinezhad, Jeffrey M Liebmann, Massimo A Fazio, Christopher A Girkin and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A Model of Progression to Help Identify Macular Damage Due to Glaucoma.Investigative ophthalmology & visual science · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takashi NishidaFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA.
Sasan MoghimiFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA.
Maya L M YamaneFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA.
Jo-Hsuan WuFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA.
Vahid MohammadzadehFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA.
Alireza KamalipourFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA.
Golnoush MahmoudinezhadFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA.
Jeffrey M LiebmannBernard and Shirlee Brown Glaucoma Research Laboratory (J.M.L.), Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Medical Center, New York, New York, USA.
Massimo A FazioFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA; Heersink School of Medicine (M.A.F., C.A.G.), University of Alabama-Birmingham, Birmingham, Alabama, USA.
Christopher A GirkinHeersink School of Medicine (M.A.F., C.A.G.), University of Alabama-Birmingham, Birmingham, Alabama, USA.
Linda M ZangwillFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA.
Robert N WeinrebFrom the Hamilton Glaucoma Center (T.N., S.M., M.L.M.Y., J.-H.W., V.M., A.K., G.M., M.A.F., L.M.Z., R.N.W.), Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California-San Diego, La Jolla, California, USA. Electronic address: rweinreb@health.ucsd.edu.

Funding

Vision BiostatisticsP30EY022589 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Derek Stuart Welsbie · 2012 to 2026
$10.3M
Diagnostic Innovations in Glaucoma:Structural AssessmentR01EY011008 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZANGWILL, LINDA M · 1995 to 2015
$8.7M
Diagnostic Innovations in Glaucoma Study (DIGS): High Myopia and Advanced DiseaseR01EY027510 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LINDA M ZANGWILL · 2017 to 2026
$5.3M
Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography AngiographyR01EY029058 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WEINREB, ROBERT N · 2018 to 2024
$4.2M
African Descent and Glaucoma Evaluation (ADAGES) II: Glaucoma ProgressionR01EY019869 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZANGWILL, LINDA M · 2010 to 2014
$2.8M
Age-related changes in optic nerve head structure and biomechanicsR01EY018926 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DOWNS, J CRAWFORD, GIRKIN, CHRISTOPHER ANTHONY · 2008 to 2015
$2.6M
African Descent and Glaucoma Evaluation (ADAGES) IV: Alterations of the lamina cribrosa in progressionR01EY026574 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FAZIO, MASSIMO ANTONIO, GIRKIN, CHRISTOPHER ANTHONY · 2017 to 2020
$2.6M
Monitoring of Glaucoma Patients in Advanced DiseaseR01EY034148 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sasan Moghimi Araghi · 2022 to 2026
$2.5M
NEI NIH HHS P30 EY022589NEI NIH HHS R01 EY011008NEI NIH HHS R01 EY018926NEI NIH HHS R01 EY019869NEI NIH HHS R01 EY026574NEI NIH HHS R01 EY027510NEI NIH HHS R01 EY029058NEI NIH HHS R01 EY034148
6 · The paper itself

Abstract

purposeTo investigate the association of vision-related quality of life (VRQOL) with the central visual field and macular ganglion cell complex (GCC) thickness in healthy control participants, patients with preperimetric glaucoma, and patients with perimetric glaucoma.

designRetrospective cross-sectional study.

methodsA total of 39 healthy, 34 preperimetric glaucoma, and 145 perimetric glaucoma patients completed the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ). A linear mixed-effect models was used to investigate the association between the glaucoma stage as measured by binocular 10-2 visual field mean sensitivity (VFMS) and GCC thickness with the Rasch-calibrated NEI-VFQ score.

resultsA total of 436 eyes from 218 participants (mean age = 67.2 [95% CI = 65.1 to 69.2] years) were enrolled. VRQOL calculated by the NEI-VFQ Rasch-calibrated score was worst for patients with perimetric glaucoma (50.7 [95% CI = 47.2 to 54.2]), followed by patients with preperimetric glaucoma (41.2 [95% CI = 34.5 to 47.9]) and healthy controls (29.3 [95% CI = 24.0 to 34.7]. Worse VRQOL had a moderate association with a worse global binocular 10-2 VFMS (-3.4 [95% CI = -5.0 to -1.9] dB per 1 score; P < .001; adjusted R

conclusionsThese findings suggest that patients with perimetric and preperimetric glaucoma have worse VRQOL than patients with healthy eyes. As compared to macular thickness measurements, the central visual field is more strongly associated with VRQOL and may better help to identify patients in need of intervention.

Indexed as

GlaucomaQuality of LifeAgedCross-Sectional StudiesFollow-Up StudiesHumansIntraocular PressureProspective StudiesRetrospective StudiesSickness Impact ProfileSurveys and QuestionnairesVisual Field Tests

Identifiers

PMID36581193
PMCPMC10038908

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.