Evidence map›Paper›PMID 36581187›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2023

Time from last immunity event against infection during Omicron-dominant period in Malaysia.

Su Lan Yang, Adiratna Mat Ripen, Jen Ven Lee, Karina Koh, Chia How Yen, Avinash Kumar Chand, Nur Aisyah Binti Abdul Rahim, Varaalakshmy Gokilavanan, Nik Nur Eliza Binti Mohamed, Raj Kumar A/L Sevalingam and 1 more

Abstract readMulticenter Study
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Su Lan YangCentre for Clinical Epidemiology, Institute for Clinical Research, National Institutes of Health, Ministry of Health Malaysia, Shah Alam, Malaysia. Electronic address: sulanyang218@gmail.com.
Adiratna Mat RipenAllergy & Immunology Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Shah Alam, Malaysia. Electronic address: adiratna@moh.gov.my.
Jen Ven LeeClinical Research Centre, Hospital Kuala Lumpur, Ministry of Health Malaysia, Kuala Lumpur, Malaysia. Electronic address: leejv85@gmail.com.
Karina KohClinical Research Centre, Hospital Kuala Lumpur, Ministry of Health Malaysia, Kuala Lumpur, Malaysia. Electronic address: karinakoh.86@gmail.com.
Chia How YenClinical Research Centre, Hospital Queen Elizabeth II, Ministry of Health Malaysia, Kota Kinabalu, Malaysia. Electronic address: skyych85@gmail.com.
Avinash Kumar ChandOccupational Health Department, Hospital Queen Elizabeth, Ministry of Health Malaysia, Kota Kinabalu, Malaysia. Electronic address: oshdoctor@gmail.com.
Nur Aisyah Binti Abdul RahimClinical Research Centre, Hospital Kuala Lumpur, Ministry of Health Malaysia, Kuala Lumpur, Malaysia. Electronic address: dr.aisyahrahim@gmail.com.
Varaalakshmy GokilavananClinical Research Centre, Hospital Kuala Lumpur, Ministry of Health Malaysia, Kuala Lumpur, Malaysia. Electronic address: varaleo24@gmail.com.
Nik Nur Eliza Binti MohamedClinical Research Centre, Hospital Kuala Lumpur, Ministry of Health Malaysia, Kuala Lumpur, Malaysia. Electronic address: elizamohamed.crc@gmail.com.
Raj Kumar A/L SevalingamClinical Research Centre, Hospital Kuala Lumpur, Ministry of Health Malaysia, Kuala Lumpur, Malaysia. Electronic address: rajkumarsevalingamcrc@gmail.com.
Kalaiarasu M PeariasamyInstitute for Clinical Research, National Institutes of Health, Ministry of Health Malaysia, Shah Alam, Malaysia. Electronic address: drkalai@moh.gov.my.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the incidence of Omicron infections in Malaysia and the exposures that could reduce the hazard of attaining Omicron infection.

methodsWe used a multicenter, prospective cohort to study 482 healthcare workers vaccinated with two and three doses of BNT162b2 for SARS-CoV-2 infection during the Omicron-dominant period in Malaysia.

resultsBetween January 31 and July 31, 2022, the cumulative incidence was 44.6% (95% CI 40.2-49.1%), and the incidence rate was 3.33 (95% CI 2.91-3.80) per 1000 person-days. Our study found that protection against Omicron infection was significantly higher for persons with previous SARS-CoV-2 infection (hazard ratio [HR] 0.41, 95% CI 0.27-0.62) and persons with a more recent immunity event (<30 days [reference] vs >90 days, HR 3.82, 95%CI 1.34-10.90) from the beginning of the Omicron period.

conclusionPre-Omicron natural infection and a recent immunity event protect against future Omicron infections.

Indexed as

BNT162 VaccineCOVID-19HumansMalaysiaProspective StudiesSARS-CoV-2BNT162 VaccineHealthcare workersHybrid immunityMalaysiaOmicronPrevious SARS-CoV-2 infectionVaccination

Identifiers

PMID36581187
PMCPMC9791788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.