Evidence map›Paper›PMID 36580157›Full record

ArticleInflammopharmacology2023

The role of adenosine receptor ligands on inflammatory pain: possible modulation of TRPV1 receptor function.

Mansour Haddad, Mohammad Alsalem, Sara A Aldossary, Heba Kalbouneh, Sahar M Jaffal, Qusai Alshawabkeh, Sa'ed Al Hayek, Omar Abdelhai, Noor A Barakat, Khalid El-Salem

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. APurinergic signalling · 2025
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  5. Article
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  7. Adenosine Receptors as Potential Therapeutic Analgesic Targets.International journal of molecular sciences · 2023
    Review
  8. Article
  9. I Feel! Therefore, I Am from Pain to Consciousness in DOC Patients.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to APharmaceuticals (Basel, Switzerland) · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Mansour HaddadFaculty of Pharmacy, Yarmouk University, Irbid, 21163, Jordan. mansour.haddad@yu.edu.jo.ORCID http://orcid.org/0000-0002-3463-7152
Mohammad AlsalemSchool of Medicine, The University of Jordan, Amman, 11942, Jordan.
Sara A AldossaryFaculty of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
Heba KalbounehSchool of Medicine, The University of Jordan, Amman, 11942, Jordan.
Sahar M JaffalBiological Sciences, Faculty of Science, The University of Jordan, Amman, 11942, Jordan.
Qusai AlshawabkehSchool of Medicine, The University of Jordan, Amman, 11942, Jordan.
Sa'ed Al HayekSchool of Medicine, The University of Jordan, Amman, 11942, Jordan.
Omar AbdelhaiAl Khalidi Hospital and Medical Center, Ibn Khaldon St.39, Amman, Jordan.
Noor A BarakatSchool of Medicine, The University of Jordan, Amman, 11942, Jordan.
Khalid El-SalemFaculty of Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.
University of Jordan · JOJordan Hospital · JOJordan University of Science and Technology · JOKing Faisal University · SAYarmouk University · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pain has a debilitating consequences on health and lifestyle. The currently available analgesics are often ineffective and accompanied by undesirable adverse effects. Although adenosine receptors (AR) activation can affect nociceptive, inflammatory, and neuropathic pain states, the specific regulatory functions of its subtypes (A

Indexed as

Antineoplastic AgentsChronic PainAnimalsCalciumMaleRatsRats, Sprague-DawleyReceptors, Purinergic P1TRPV Cation ChannelsAntineoplastic AgentsCalciumReceptors, Purinergic P1Trpv1 protein, ratTRPV1 receptorTRPV Cation ChannelsAdenosine receptorsInflammationPainTRPV1

Identifiers

PMID36580157
OpenAlexW4313280020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.