ArticleNeuroradiology2023
Congenital isolated unilateral third nerve palsy in children: the diagnostic contribution of high-resolution MR imaging.
Article in Neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 7 citations in OpenAlex.
- Presumed Pediatric Isolated Oculomotor Nerve Schwannoma - A Case Report.International medical case reports journal · 2025Article
- Radiologic Imaging in Third Nerve Palsy: A Case Series Investigating Etiology, Patterns, and Clinical Implications.Cureus · 2023Article
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
Abstract
purposeTo describe the neuroanatomical correlates of unilateral congenital isolated oculomotor palsy by means of high-resolution MRI.
methodsChildren with a clinical diagnosis of congenital isolated oculomotr palsy and with a high-resolution MRI acquisition targeted on the orbits and cranial nerves were selected and included in the study. An experienced pediatric neuroradiologist evaluated all the exams, assessing the integrity and morphology of extraocular muscles, oculomotor, trochlear and abducens nerves as well as optic nerves and globes. Clinical data and ophthalmologic evaluations were also collected.
resultsSix children (age range: 1-16 years; males: 3) were selected. All patients showed, on the affected side (left:right = 5:1), anomalies of the III nerve and extraocular muscles innervated by the pathological nerve. One patient had complete nerve agenesis, two patients showed a diffuse thinning of the nerve, from the brainstem to the orbit and 3 patients showed a distal thinning of the oculomotor nerve, starting at the level of the cavernous sinus. In all cases atrophy of corresponding muscles was noticed, but the involvement of the affected muscles varied with the nervous pattern of injury.
conclusionsHigh-resolution MRI represents a valuable tool for the diagnosis of III nerve anomalies in unilateral congenital IOP, showing different patterns of nerve involvement and muscular atrophy.
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