ArticleeLife2022
Inducible lncRNA transgenic mice reveal continual role of
Open access · goldAbstract read
In one paragraph
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 44 citations in OpenAlex.
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- Noncoding RNA in Clinical Trials: Diagnostic and Therapeutical Prospects.Experientia supplementum (2012) · 2026Review
- Mapping Non-Coding Epimutations in Breast Cancer: Advancing Epigenetics Towards Precision Medicine.Sub-cellular biochemistry · 2026Review
- LncRNA-Histone Modification Crosstalk: Orchestrating Cancer Pathobiology.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- The crucial role of circadian synchronization in bone marrow adipose tissue mesenchymal stem cells: insights into pathogenesis in Fanconi anemia and acute myeloid leukemia.Molecular biology reports · 2025Article
- The role of genetics and epigenetics in breast cancer: A comprehensive review of metastasis, risk factors, and future perspectives.Journal of pharmaceutical analysis · 2025Review
- The Role of Non-Coding Regions in Breast Cancer: From Gene Regulation to Therapeutic Implications.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Cancer stem cells and Lon-noncRNA promotes invasion, metastasis and tumor growth in breast cancer through regulation of signaling pathway.Scientific reports · 2025Article
- [Targeting chimera technology: A new tool for undruggable in breast cancer].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Review
- Potential regulatory role of the mActa biochimica et biophysica Sinica · 2025Review
- METTL3: a multifunctional regulator in diseases.Molecular and cellular biochemistry · 2025Review
- Mechanisms of breast cancer metastasis: the role of extracellular matrix.Molecular and cellular biochemistry · 2025Review
- Noncoding RNAs, Vital Players in Breast Cancer Metastasis.Breast cancer (Dove Medical Press) · 2025Review
- OTUD6B-AS1: a multifaceted regulator of cancer with critical clinical implications.American journal of cancer research · 2025Review
- Chromatin accessibility: biological functions, molecular mechanisms and therapeutic application.Signal transduction and targeted therapy · 2024Review
- Fer-mediated activation of the Ras-MAPK signaling pathway drives the proliferation, migration, and invasion of endometrial carcinoma cells.Molecular and cellular biochemistry · 2024Article
- Approaches to probe and perturb long noncoding RNA functions in diseases.Current opinion in genetics & development · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 6 institutions in 5 countries.
Qing Ma *Shenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID 0000-0002-8361-5275
Liuyi Yang *Shenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID 0000-0001-5405-6411
Karen Tolentino *Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, United States.
Guiping WangCenter for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, United States.
Yang ZhaoCenter for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, United States.
Ulrike M LitzenburgerCenter for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, United States.
Quanming ShiCenter for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, United States.
Lin ZhuShenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Chen YangDepartment of Histoembryology, Genetics and Developmental Biology, Shanghai Key Laboratory of Reproductive Medicine, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education，Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huiyuan JiaoDepartment of Histoembryology, Genetics and Developmental Biology, Shanghai Key Laboratory of Reproductive Medicine, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education，Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Feng ZhangDepartment of Histoembryology, Genetics and Developmental Biology, Shanghai Key Laboratory of Reproductive Medicine, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education，Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Rui LiCenter for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, United States.
Miao-Chih TsaiCenter for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, United States.
Jun-An ChenInstitute of Molecular Biology, Academia Sinica, Taipei, Taiwan.ORCID 0000-0001-9870-3203
Ian LaiTransgenic, Knockout, and Tumor Model Center, Stanford University School of Medicine, Stanford, United States.ORCID 0000-0001-8662-7290
Hong ZengTransgenic, Knockout, and Tumor Model Center, Stanford University School of Medicine, Stanford, United States.
Lingjie LiDepartment of Histoembryology, Genetics and Developmental Biology, Shanghai Key Laboratory of Reproductive Medicine, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education，Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-4348-516X
Howard Y ChangCenter for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, United States.ORCID 0000-0002-9459-4393
Dynamic Imaging (United Kingdom) · GBShanghai Jiao Tong University · CNChinese Academy of Sciences · CNCancer Institute (WIA) · INHoward Hughes Medical Institute · USInstitute of Molecular Biology, Academia Sinica · TW
Funding
LncRNA mechanisms in cancerR35CA209919 · NCI · STANFORD UNIVERSITY · PI CHANG, HOWARD Y · 2016 to 2022
$6.4MHoward Hughes Medical InstituteNCI NIH HHS R35 CA209919
Abstract
PubMed holds no abstract for this paper.
Indexed as
Breast NeoplasmsRNA, Long NoncodingAnimalsCell Line, TumorCell ProliferationChromatinFemaleGene Expression RegulationGene Expression Regulation, NeoplasticHumansLung NeoplasmsMiceMice, TransgenicChromatinHOTAIR long untranslated RNA, humanRNA, Long Noncodingbreast cancercancer biologychromatinchromosomesepigeneticsgene expressiongenetically engineered mouse modellncRNAmetastasismouse
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.