Evidence map›Paper›PMID 36579640›Full record

ReviewStroke2023

Ambient Air Pollution and Stroke: An Updated Review.

Erin R Kulick, Joel D Kaufman, Coralynn Sack

Open access · bronzeAbstract readReview
In one paragraph

Review in Stroke, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 131 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. From fatal events to chronic disability: The evolving clinical landscape of PM2.5-attributable hemorrhagic stroke in China (1990-2050).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Association of PMRespiratory research · 2026
    Article
  18. Article
  19. Weathering the storm: Effect of climate change on acute stroke care and stroke rehabilitation.PM & R : the journal of injury, function, and rehabilitation · 2026
    Review
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Erin R KulickDepartment of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA (E.R.K.).ORCID 0000-0001-8650-5357
Joel D KaufmanDepartment of Medicine, University of Washington, Seattle (J.D.K., C.S.).ORCID 0000-0003-4174-9037
Coralynn SackDepartment of Medicine, University of Washington, Seattle (J.D.K., C.S.).
University of Washington · USTemple University · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Nicole Ann Errett · 1995 to 2026
$42.5M
The Role of Airway Morphology in Environmental LungDiseasesK23ES030725 · NIEHS · UNIVERSITY OF WASHINGTON · PI SACK, CORALYNN SHAYNA · 2019 to 2023
$835k
NIEHS NIH HHS K23 ES030725NIEHS NIH HHS P30 ES007033
6 · The paper itself

Abstract

Despite recent advances in treatment and prevention, stroke remains a leading cause of morbidity and mortality. There is a critical need to identify novel modifiable risk factors for disease, including environmental agents. A body of evidence has accumulated suggesting that elevated levels of ambient air pollutants may not only trigger cerebrovascular events in susceptible people (short-term exposures) but also increase the risk of future events (long-term average exposures). This review assesses the updated evidence for both short and long-term exposure to ambient air pollution as a risk factor for stroke incidence and outcomes. It discusses the potential pathophysiologic mechanisms and makes recommendations to mitigate exposure on a personal and community level. The evidence indicates that reduction in air pollutant concentrations represent a significant population-level opportunity to reduce risk of cerebrovascular disease.

Indexed as

Air PollutantsAir PollutionStrokeEnvironmental ExposureHumansNitrogen DioxideParticulate MatterRisk FactorsAir PollutantsNitrogen DioxideParticulate Matterair pollutionlungnitric oxidenitrogen dioxideparticulate mattersmokestroke

Identifiers

PMID36579640
PMCPMC10421613
OpenAlexW4313279468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.