Evidence map›Paper›PMID 36579565›Full record

ArticleJournal of personalized medicine2022

The Differential Systemic Biological Effects between Computer Navigation and Conventional Total Knee Arthroplasty (TKA) Surgeries: A Prospective Study.

Shu-Jui Kuo, Ka-Kit Siu, Kuan-Ting Wu, Jih-Yang Ko, Feng-Sheng Wang

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shu-Jui KuoSchool of Medicine, China Medical University, Taichung 404, Taiwan.ORCID 0000-0002-2992-4608
Ka-Kit SiuDepartment of Orthopedic Surgery, Park One International Hospital, Kaohsiung 813, Taiwan.
Kuan-Ting WuDepartment of Orthopedic Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.
Jih-Yang KoDepartment of Orthopedic Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.ORCID 0000-0001-7136-6550
Feng-Sheng WangDepartment of Medical Research, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

Funding

China Medical University Hospital, Taiwan DMR-110-111China Medical University Hospital, Taiwan DMR-110-224China Medical University Hospital, Taiwan DMR-111-114China Medical University Hospital, Taiwan DMR-111-230Kaohsiung Chang Gung Memorial Hospital, Taiwan CRRPG8J0071~3Minister of Science and Technology, Taiwan 109-2314-B-039-018-MY3Minister of Science and Technology, Taiwan 110-2314-B-182A-149-Minister of Science and Technology, Taiwan 111-2314-B-182A-055-
6 · The paper itself

Abstract

Distal femur reaming-free total knee arthroplasty (TKA) was reported to possess lower risk of acute myocardial infarction (AMI) or venous thromboembolism (VTE) than conventional TKA in a retrospective population-based study. We tried to offer prospective biological evidence by comparing the levels of AMI and VTE serum surrogate markers among the patients undertaking navigation and conventional TKAs to support these observations. Thirty-four participants undertaking navigation TKA and 34 patients receiving conventional TKA were recruited between February 2013 and December 2015. Blood samples were drawn from all participants before TKA, and 24 and 72 h after TKA, to assess the concentration of soluble P-selectin, matrix metalloproteinase-9 (MMP-9), C-reactive protein (CRP), and interleukin-8 (IL-8) between the participants undergoing navigation and conventional TKAs. We showed that significantly lower serum levels of soluble P-selectin 24 h after, as well as CRP 24 and 72 h after TKA could be observed in the navigation cohort. The more prominent surge of serum soluble P-selectin and CRP were perceived 24 and 72 h after TKA among the participants undergoing conventional TKA. Based upon our prospective biological evidence, the merits of navigation TKA are strengthened by lower levels of AMI and VTE serum surrogate markers.

Indexed as

C-reactive protein (CRP)interleu-kin-8 (IL-8)matrix metalloproteinase-9 (MMP-9)navigation TKAsoluble P-selectintotal knee arthroplasty (TKA)

Identifiers

PMID36579565
PMCPMC9696737

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.