Evidence map›Paper›PMID 36579547›Full record

ArticleJournal of personalized medicine2022

[

Alberto Signore, Chiara Lauri, Maria Paola Bianchi, Sabrina Pelliccia, Andrea Lenza, Simone Tetti, Maria Luisa Martini, Gabriele Franchi, Fabio Trapasso, Luciano De Biase and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. The additional value ofRespiratory research · 2024
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Alberto SignoreNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-8923-648X
Chiara LauriNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-0314-5059
Maria Paola BianchiHaematology, "Sant'Andrea" University Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Sabrina PellicciaHaematology, "Sant'Andrea" University Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Andrea LenzaNuclear Medicine Unit, AOU Sant'Andrea, 00189 Rome, Italy.
Simone TettiNuclear Medicine Unit, AOU Sant'Andrea, 00189 Rome, Italy.
Maria Luisa MartiniNuclear Medicine Unit, AOU Sant'Andrea, 00189 Rome, Italy.
Gabriele FranchiNuclear Medicine Unit, AOU Sant'Andrea, 00189 Rome, Italy.
Fabio TrapassoNuclear Medicine Unit, AOU Sant'Andrea, 00189 Rome, Italy.
Luciano De BiaseHeart Failure Unit, Department of Clinical and Molecular Medicine, Sapienza University of Rome, 00189 Rome, Italy.ORCID 0000-0001-7739-3197
Antonio AcetiInfection Unit, Department NESMOS, Sapienza University of Rome, 00185 Rome, Italy.
Agostino TafuriHaematology, "Sant'Andrea" University Hospital, Sapienza University of Rome, 00189 Rome, Italy.
CTO Andrea Alesini · ITSapienza University of Rome · ITAzienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesInterstitial pneumonia is a severe complication induced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Several treatments have been proposed alone or, more often, in combination, depending, also, on the presence of other organ disfunction. The most frequently related, well-described, and associated phenomenon is pan-lymphopenia with circulating, high levels of cytokines. We report, here, on two patients with COVID-19 and lymphoproliferative disorders treated with Tocilizumab (a humanized monoclonal antibody against the interleukin-6 receptor) and followed by an [

methodsOne patient with angioimmunoblastic T-lymphoma (A), one with Hodgkin lymphoma (A), and both with positive RT-PCR for SARS-CoV-2 and with similar clinical findings of interstitial pneumonia at the CT scan, were imaged by [

resultsIn both patients, the basal [

conclusionsIn conclusion, in these two patients, interstitial pneumonia was efficiently treated with Tocilizumab, as demonstrated by the [

Indexed as

[18F]FDG PET/CTCOVID-19pneumoniaSARS-CoV-2tocilizumab

Identifiers

PMID36579547
PMCPMC9692335
OpenAlexW4308203719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.