ArticleCureus2022
Bone Cement Implantation Syndrome: Incidence and Associated Factors in a United States Setting.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- [Expert consensus on the application of bone cement in the treatment of diabetic wounds (2026 edition)].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- Article
- Bone cement implantation syndrome: a scoping review.British journal of anaesthesia · 2025Article
- Bone cement implantation syndrome in patients with cemented endoprostheses for metastatic bone disease in the femur.Journal of bone oncology · 2025Article
- Hypermagnesemia- and Hyperphosphatemia-Associated Cardiac Arrest after Injection of a Novel Magnesium-Based Bone Cement in Spinal Surgery.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Hemodynamic Effects of Bone Cement Implantation in Hip Arthroplasty: Insights from a Prospective Study in Eastern India.Journal of orthopaedic case reports · 2024Article
- Comparative assessment of bone cement implantation syndrome in cemented bipolar hemiarthroplasty: impact in patients with and without preexisting heart disease.Orthopedic reviews · 2024Article
- Biodegradable Cements for Bone Regeneration.Journal of functional biomaterials · 2023Review
- The Incidence of Bone Cement Implantation Syndrome Grade 3 in Hip and Knee Arthroplasty: A Retrospective Multicenter Case Series.JB & JS open accessArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of bone cement implantation syndrome (BCIS) following cemented hemiarthroplasty for the treatment of hip fracture in the United States (US) population is not previously described. We sought to describe the incidence and factors associated with BCIS as well as its impact on mortality.
methodsIn this retrospective observational study, electronic health records were examined for all relevant cases and BCIS was identified and graded according to accepted criteria. Demographic data was collected and an adjusted Cox proportional model was performed to determine the impact of severe BCIS on mortality.
resultsFollowing exclusions for documentation error and misclassification, 69 patients were included in the final analysis. BCIS, regardless of grade, was present in 24 (35%) patients, while severe BCIS (grades 2 and 3) was found in 7 (10%) of patients. Cox proportional hazard estimation adjusted for American Society of Anesthesiologists (ASA) grade, male sex, and age did not show severe BCIS to be independently associated with mortality, hazard ratio (CI) 1.96 (0.22-17.22).
conclusionThe incidence of BCIS in a selected hip fracture population is comparable in the US to those found in European studies. This study did not establish the occurrence of BCIS with mortality. As cemented hemiarthroplasty is recommended for displaced hip fractures and its use escalates in the US, one can expect an increase in the absolute number of patients experiencing BCIS as well.
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