ArticleNorth American Spine Society journal2023
The 5-factor modified Frailty Index (mFI-5) predicts adverse outcomes after elective Anterior Lumbar Interbody Fusion (ALIF).
Article in North American Spine Society journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 23 citations in OpenAlex.
- Baseline history of primary fragility fracture is associated with medical complications and revision through 1 year in adult spinal deformity patients undergoing thoracolumbar spinal fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Predictive value of the 5-factor modified frailty index for pneumonia in older adults with cervical spinal cord injury.Spinal cord · 2026Article
- Risk Analysis Index Versus mFI-5 for Predicting Outcomes After Uvulopalatopharyngoplasty.The Laryngoscope · 2026Article
- The Utility and Applicability of the Modified 5-Item Frailty Index in Cosmetic Surgery.Aesthetic plastic surgery · 2026Article
- Factors Associated With Reoperation After Minimally Invasive Tubular Transforaminal Lumbar Interbody Fusion: A Cohort Study of 756 Patients.Global spine journal · 2026Article
- Frailty (mFI-5) and Age Predict Medical Complications After Posterior Lumbar Interbody Fusion in Older Adults: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Early (<24 hours) venous thromboembolism prophylaxis in traumatic brain injury: development of the EViTBI algorithm using a national cohort.Trauma surgery & acute care open · 2026Article
- Feasibility of local anesthesia for full-endoscopic spine surgery: A retrospective cohort study of body weight-based thresholds.PloS one · 2026Article
- Frailty as an Independent predictor of perioperative risk and recovery in long-segment thoracolumbar fusion surgery: A retrospective cohort study.North American Spine Society journal · 2025Article
- Impact of frailty on short- and long-term outcomes following cervical laminoplasty for ossification of the posterior longitudinal ligament: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Influence of Frailty on Clinical and Radiological Outcomes in Patients Undergoing Transforaminal Lumbar Interbody Fusion-Analysis of a Controlled Cohort of 408 Patients.Journal of clinical medicine · 2025Article
- The 5-Factor Modified Frailty Index is Associated With Increased Risk of Reoperations and Adjacent Level Disease Following Single-Level Transforaminal Lumbar Interbody Fusion.Global spine journal · 2025Article
- Emerging Healthcare Trends in Prosthetic Treatment of Hand Osteoarthritis.Journal of clinical medicine · 2025Article
- The biomechanical effects of treating double-segment lumbar degenerative diseases with unilateral fixation through interlaminar fenestration interbody fusion surgery: a three-dimensional finite element study.BMC musculoskeletal disorders · 2025Article
- Utility of the mFI-5 as a predictor of post-operative outcomes following gastrectomy for gastric cancer: an ACS-NSQIP analysis.Surgical endoscopy · 2024Article
- The 5-factor modified frailty index (mFI-5) predicts adverse outcomes after elective anterior cervical discectomy and fusion (ACDF).North American Spine Society journal · 2024Article
- Higher Modified Frailty Index Score is Associated with Increased 30-Day Postoperative Complications Following Surgical Treatment of Tibial Shaft Fractures.The archives of bone and joint surgery · 2024Article
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10 authors at 2 institutions in 1 country.
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Abstract
Background: The 5-factor modified frailty index (mFI-5) has been shown to be a concise and effective tool for predicting adverse events following various spine procedures. However, there have been no studies assessing its utility in patients undergoing anterior lumbar interbody fusion (ALIF). Therefore, the aim of this study was to analyze the predictive capabilities of the mFI-5 for 30-day postoperative adverse events following elective ALIF. Methods: The National Surgical Quality Improvement Program (NSQIP) database was queried from 2010 through 2019 to identify patients who underwent elective ALIF using Current Procedural Terminology (CPT) codes in patients over the age of 50. The mFI-5 score was calculated using variables for hypertension, congestive heart failure, comorbid diabetes, chronic obstructive pulmonary disease, and partially or fully dependent functional status which were each assigned 1 point. Univariate analysis and multivariate logistic regression models were utilized to identify the associations between mFI-5 scores, and 30-day rates of overall complications, readmissions, reoperations, and mortality. Results: 11,711 patients were included (mFI-5=0: 4,026 patients, mFI-5=1: 5,392, mFI-5=2: 2,102, mFI-5=3+: 187. Multivariate logistic regression revealed that mFI-5 scores of 1 (OR: 2.2, CI: 1.2-4.2, p=0.02), 2 (OR: 3.6, CI: 1.8-7.3, p<0.001), and 3+ (OR: 7.0, CI: 2.5-19.3, p<0.001) versus a score of 0 were significant predictors of pneumonia. An mFI-5 score of 2 (OR: 1.3; CI: 1.01-1.6, p=0.04), and 3+ (OR: 1.9; CI: 1.1-3.1; p=0.01) were both independent predictors of related readmissions. An mFI score of 3+ was an independent predictor of any complication (OR: 1.5, CI: 1.01-2.2, p=0.004), UTI (OR: 2.4, CI: 1.1-5.2, p=0.02), and unplanned intubation (OR: 4.5, CI: 1.3-16.1, p=0.02). Conclusions: The mFI-5 is an independent predictor for 30-day postoperative complications, readmissions, UTI, pneumonia, and unplanned intubations following elective ALIF surgery in adults over the age of 50.
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