Evidence map›Paper›PMID 36579154›Full record

ArticleFrontiers in medicine2022

Case report: Hemorrhagic fever with renal syndrome presenting as hemophagocytic lymphohistiocytosis.

Maarten A J De Smet, Simon Bogaert, Alexander Schauwvlieghe, Amélie Dendooven, Pieter Depuydt, Patrick Druwé

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Increased blood CD226Annals of medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maarten A J De SmetDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
Simon BogaertDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
Alexander SchauwvliegheDepartment of Hematology, Ghent University Hospital, Ghent, Belgium.
Amélie DendoovenDepartment of Pathology, Ghent University Hospital, Ghent, Belgium.
Pieter DepuydtDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
Patrick DruwéDepartment of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
Ghent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophagocytic lymphohistiocytosis may occur in patients with genetic predisposition and in sporadic cases due to malignancy or infection. We describe a 49-year old man with hemorrhagic fever, type 1 respiratory insufficiency and acute kidney injury. Diagnostic work up showed a hyperinflammatory syndrome, hypertriglyceridemia, hemophagocytosis, very high ferritin and significantly elevated sCD25. The findings were compatible with hemophagocytic lymphohistiocytosis based on the HLH-2004 criteria. Serological testing indentified

Indexed as

communicable diseases Puumala virus-associated hemophagocytosiscritical carehantavirushemophagocytic lymphohistiocytosishemorrhagic fever with renal syndrome

Identifiers

PMID36579154
PMCPMC9790895
OpenAlexW4311127412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.