Evidence map›Paper›PMID 36579132›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2022

Life satisfaction across the entire trajectory of Alzheimer's disease: A mediation analysis.

Arenda Mank, Ingrid S van Maurik, Argonde C van Harten, Hanneke F M Rhodius-Meester, Charlotte E Teunissen, Bart N M van Berckel, Johannes Berkhof, Wiesje M van der Flier, Judith J M Rijnhart

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Arenda MankAlzheimer Center Amsterdam, Neurology Amsterdam UMC location VUmc Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Ingrid S van MaurikAlzheimer Center Amsterdam, Neurology Amsterdam UMC location VUmc Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Argonde C van HartenAlzheimer Center Amsterdam, Neurology Amsterdam UMC location VUmc Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Hanneke F M Rhodius-MeesterAlzheimer Center Amsterdam, Neurology Amsterdam UMC location VUmc Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Charlotte E TeunissenNeurochemistry Laboratory Department of Clinical Chemistry Amsterdam UMC location VUmc Vrije Universiteit Amsterdam The Netherlands.
Bart N M van BerckelAlzheimer Center Amsterdam, Neurology Amsterdam UMC location VUmc Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Johannes BerkhofAmsterdam UMC, Vrije Universiteit Amsterdam Department of Epidemiology and Data Science Amsterdam Public Health Institute Amsterdam The Netherlands.
Wiesje M van der FlierAlzheimer Center Amsterdam, Neurology Amsterdam UMC location VUmc Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Judith J M RijnhartAmsterdam UMC, Vrije Universiteit Amsterdam Department of Epidemiology and Data Science Amsterdam Public Health Institute Amsterdam The Netherlands.
Amsterdam Neuroscience · NLAmsterdam University Medical Centers · NLVrije Universiteit Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: We studied life satisfaction across Alzheimer's disease (AD) stages and studied mobility and meaningful activities as mediators of the associations between these AD stages and life satisfaction. Methods: In this cross-sectional study, we included Results: Patients with dementia are less satisfied with life compared to SCD and MCI. These differences in life satisfaction are explained by reduced participation in meaningful activities, which in turn, was largely attributable to decreased transportation use. Discussion: Our findings suggest that improving access to transportation, therewith allowing participation in meaningful activities help to maintain life satisfaction and may be an important target for intervention.

Indexed as

Alhzeimer's diseasedementialife satisfactionmild cognitive impairmentmobilitysubjective cognitive decline

Identifiers

PMID36579132
PMCPMC9780509
OpenAlexW4312395983

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.