Evidence map›Paper›PMID 36578935›Full record

ArticleFrontiers in oncology2022

Determination of a cost-effectiveness threshold for cancer interventions in Iran.

Hossein Safari, Thomas G Poder, Somayeh Afshari, Azin Nahvijou, Morteza Arab-Zozani, Nasrin Moradi, Hosein Ameri

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Willingness to pay for a quality adjusted life year across different time horizons: direct elicitation in Quebec.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  2. Willingness to pay for a quality-adjusted life year in Iran: a systematic review.Cost effectiveness and resource allocation : C/E · 2026
    Review
  3. Article
  4. Review
  5. Valuing the SF-6Dv2 in the capital of Iran using a discrete choice experiment with duration.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  6. Article
  7. A national survey of Iranian general population to estimate a value set for the EQ-5D-5L.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hossein SafariHealth Promotion Research Centre, Iran University of Medical Sciences, Tehran, Iran.
Thomas G PoderDepartment of Management, Evaluation and Health Policy, School of Public Health, University of Montreal, Montreal, QC, Canada.
Somayeh AfshariDepartment of Health Management and Economics, School of Public Health, Tehran University of Medical Science, Tehran, Iran.
Azin NahvijouCancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Morteza Arab-ZozaniSocial Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Nasrin MoradiDepartment of Health Management and Economics, School of Public Health, Iran University of Medical Science, Tehran, Iran.
Hosein AmeriHealth Policy and Management Research Center, Department of Health Management and Economics, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: The estimation of a cost- Effectiveness (CE) threshold from the perspective of those who have experienced a life-threatening disease can provide empirical evidence for health policy makers to make the best allocation decisions on limited resources. The aim of the current study was to empirically determine the CE threshold for cancer interventions from the perspective of cancer patients in Iran. Methods: A composite time trade-off (cTTO) task for deriving quality adjusted life-year (QALY) and a double-bounded dichotomous choice (DBDC) approach followed by open-ended question for examining patients' willingness-to-pay were performed. A nationally representative sample of 580 cancer patients was recruited from the largest governmental cancer centers in Iran between June 2021 and January 2022, and data were gathered using face-to-face interviews. The CE threshold was calculated using the nonparametric Turnbull model and parametric interval-censored Weibull regression model. Furthermore, the factors that affect the CE threshold were determined using the parametric model. Results: The estimated CE threshold using the nonparametric Turnbull model and parametric interval-censored Weibull regression model was IRR 440,410,000 (USD 10,485.95) and IRR 595,280,000 (USD 14,173.33) per QALY, respectively. Gender, age, education, income, type of cancer, and current treatment status were significantly associated with the estimated CE threshold. Conclusions: The value of parametric model-based threshold in this study was 1.98 times the Iranian GDP per capita, which was lower than the CE threshold value recommended by the WHO (i.e., 3 times the GDP per capita) for low-and middle-income countries.

Indexed as

cancer patientscost-effectiveness thresholdIranquality-adjusted life-yearwillingness to pay

Identifiers

PMID36578935
PMCPMC9791211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.