Evidence map›Paper›PMID 36578919›Full record

SynthesisGlobal heart2022

The Effect of Cardiac Rehabilitation on Lipid Levels in Patients with Coronary Heart Disease. A Systematic Review and Meta-Analysis.

Gang Wu, Yemei Hu, Kun Ding, Xuedong Li, Jun Li, Zhuo Shang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Global heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Effect of Cardiac Rehabilitation on Cardiovascular Events in Patients With Advanced Chronic Kidney Disease.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Cardiac Rehabilitation Increases Plasma Klotho Levels.Journal of clinical medicine · 2024
    Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gang WuDepartment of Cardiology, Bengbu second people's hospital, Bengbu, Anhui province, 233000, PR, China.ORCID 0000-0002-8026-2435
Yemei HuDepartment of Cardiology, Bengbu second people's hospital, Bengbu, Anhui province, 233000, PR, China.ORCID 0000-0002-7575-2480
Kun DingDepartment of Cardiology, Bengbu second people's hospital, Bengbu, Anhui province, 233000, PR, China.ORCID 0000-0001-6513-4382
Xuedong LiDepartment of Cardiology, Bengbu second people's hospital, Bengbu, Anhui province, 233000, PR, China.ORCID 0000-0002-7391-575X
Jun LiDepartment of Cardiology, Bengbu second people's hospital, Bengbu, Anhui province, 233000, PR, China.ORCID 0000-0002-4037-6526
Zhuo ShangBengbu second people's hospital, No. 302 of Yan' an Road, Bengbu, Anhui province, 233000, PR, China.ORCID 0000-0002-1262-6364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac rehabilitation (CR) is a multidisciplinary medical program. Most studies have emphasized the effect of exercise-based CR in lowering lipid levels; however, the effect of CR as a comprehensive program on lipid levels remains unclear. Methods: Electronic database were searched up to 2022. Randomized controlled trials with lipid profile indicators were included. Standardized mean differences (SMDs) and 95% CIs were used to evaluate the effect size. Begg's funnel plot and Egger's linear regression test were used to assess publication bias. Results: CR remarkably reduced low-density lipoprotein cholesterol (LDL-C) levels (SMD = -0.23; 95%CI: [-0.38, -0.08]; P < 0.001), triglyceride (TG) levels (SMD = -0.17; 95%CI: [-0.28, -0.06]; P < 0.001), and total cholesterol (TC) levels (SMD = -0.30; 95%CI: [-0.43, -0.16]; P < 0.001) and increased high-density lipoprotein cholesterol (HDL-C) levels (SMD = 0.19; 95%CI: [0.10, 0.29]; P < 0.001). Conclusions: CR reduce TC, TG, and LDL-C levels while improving HDL-C levels. CR should be promoted and more trials should be conducted for long-term CR.

Indexed as

Cardiac RehabilitationCoronary DiseaseCholesterol, HDLCholesterol, LDLHumansTriglyceridesCholesterol, HDLCholesterol, LDLTriglyceridesCoronary diseasecoronary disease rehabilitationlipid profilerandomized controlled trials

Identifiers

PMID36578919
PMCPMC9717003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.