Evidence map›Paper›PMID 36578864›Full record

ReviewWorld journal of diabetes2022

Non-coding RNAs: Role in diabetic foot and wound healing.

Yi-Bo Tang, Muhuza Marie Parfaite Uwimana, Shu-Qi Zhu, Li-Xia Zhang, Qi Wu, Zhao-Xia Liang

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yi-Bo TangDepartment of Obstetrics, Women's Hospital School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang Province, China.
Muhuza Marie Parfaite UwimanaDepartment of Obstetrics, Women's Hospital School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang Province, China.
Shu-Qi ZhuDepartment of Obstetrics, Women's Hospital School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang Province, China.
Li-Xia ZhangDepartment of Obstetrics, Women's Hospital School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang Province, China.
Qi WuDepartment of Obstetrics, Women's Hospital School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang Province, China.
Zhao-Xia LiangDepartment of Obstetrics, Women's Hospital School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang Province, China. xiaozaizai@zju.edu.cn.
Women's Hospital, School of Medicine, Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic foot ulcer (DFU) and poor wound healing are chronic complications in patients with diabetes. The increasing incidence of DFU has resulted in huge pressure worldwide. Diagnosing and treating this condition are therefore of great importance to control morbidity and improve prognosis. Finding new markers with potential diagnostic and therapeutic utility in DFU has gathered increasing interest. Wound healing is a process divided into three stages: Inflammation, proliferation, and regeneration. Non-coding RNAs (ncRNAs), which are small protected molecules transcribed from the genome without protein translation function, have emerged as important regulators of diabetes complications. The deregulation of ncRNAs may be linked to accelerated DFU development and delayed wound healing. Moreover, ncRNAs can be used for therapeutic purposes in diabetic wound healing. Herein, we summarize the role of microRNAs, long ncRNAs, and circular RNAs in diverse stages of DFU wound healing and their potential use as novel therapeutic targets.

Indexed as

Circular RNAsDiabetic foot ulcerInflammationLong non-coding RNAsMicroRNAProliferationRegenerationWound healing

Identifiers

PMID36578864
PMCPMC9791568
OpenAlexW4311418217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.