Evidence map›Paper›PMID 36578845›Full record

ArticleCureus2022

A Rare Case of Aggressive Atypical Cervical Cancer With Multi-Organ Involvement.

Carina Hernandez, Alanna Glidden, Michael Sandhu, Kavita Agrawal, Martha Caicedo Murillo, Claudia Heritage, Merima Ramovic, Komal Akhtar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. When Metastatic Cervical Cancer Presents as Miliary Lung Nodules.European journal of case reports in internal medicine · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carina HernandezInternal Medicine, Upstate University Hospital, Syracuse, USA.
Alanna GliddenInternal Medicine, Upstate University Hospital, Syracuse, USA.
Michael SandhuInternal Medicine, Upstate University Hospital, Syracuse, USA.
Kavita AgrawalHematology and Oncology, Upstate University Hospital, Syracuse, USA.
Martha Caicedo MurilloPathology, Upstate University Hospital, Syracuse, USA.
Claudia HeritageInternal Medicine, Upstate University Hospital, Syracuse, USA.
Merima RamovicHematology and Oncology, Upstate University Hospital, Syracuse, USA.
Komal AkhtarHematology and Oncology, Upstate University Hospital, Syracuse, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Squamous cell carcinoma (SCC) of cervical origin with metastasis to the brain is rare. Our patient was a 30-year-old Caucasian female with squamous cell carcinoma, initially with unknown primary, with metastases to the brain, kidney, cervix, lung, adrenal glands, vulva, pelvic wall, and scalp. She initially presented to her outpatient gynecologist for a vulvar mass. A biopsy of the vulvar mass was consistent with SCC. The patient continued to have fatigue along with thoracic rib pain. An initial work-up was performed, including imaging which showed diffuse metastatic disease involving the lungs, kidneys and adrenal glands, as well as a pathological compression fracture of the seventh thoracic vertebra with cord compression. Brain magnetic resonance imaging (MRI) showed multiple metastatic lesions and she underwent craniotomy for brain lesion resection. Given the aggressive nature of the patient's disease and her symptomatic burden, she was started on chemotherapy in the hospital with Carboplatin, Paclitaxel, and Pembrolizumab.

Indexed as

brain metastasiscervical cancerhpvmulti-organsquamous cell carcinoma

Identifiers

PMID36578845
PMCPMC9792719

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.