Evidence map›Paper›PMID 36578814›Full record

ArticleThe Pan African medical journal2022

Can pelvic radiotherapy induce a leiomyosarcoma of the prostate? (A case report).

Saad Bkiri, Zakaria Tlemsani, Youness Khdach, Karim Bennani, Fayçal Abbad, Mohammed Ghadouane

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Saad BkiriUrology Department, Cheikh Zaid International Hospital, Abulcasis International University, Rabat, Morocco.
Zakaria TlemsaniUrology Department, Cheikh Zaid International Hospital, Abulcasis International University, Rabat, Morocco.
Youness KhdachUrology Department, Cheikh Zaid International Hospital, Abulcasis International University, Rabat, Morocco.
Karim BennaniUrology Department, Cheikh Zaid International Hospital, Abulcasis International University, Rabat, Morocco.
Fayçal AbbadHistopathology Department, Cheikh Zaid International Hospital, Abulcasis International University, Rabat, Morocco.
Mohammed GhadouaneUrology Department, Cheikh Zaid International Hospital, Abulcasis International University, Rabat, Morocco.
International University of Rabat · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leiomyosarcoma of the prostate is an extremely rare neoplasm. It represents less than 0.1% of all prostate malignancies. It is considered to have a poor prognosis, an aggressive nature, and high metastatic potential. Additionally, the relationship between radiation exposure for the treatment of primary prostatic cancer and the occurrence of leiomyosarcoma as second cancer at the irradiated site is rare, with unknown etiology. We reported a 72-year-old male known case of prostate adenocarcinoma with radio-hormonotherapy for six years who presented with acute urinary retention. Magnetic resonance imaging revealed a large malignant obstructive prostate with direct invasion of surrounding organs and multiple metastases. Trans-urethral resection of the prostate was performed, and the histopathology result showed high-grade leiomyosarcoma. The patient passed away after four months due to multiorgan failure. In conclusion, there may be a causal relationship between radiation therapy to the prostate and the development of prostate leiomyosarcoma.

Indexed as

LeiomyosarcomaProstatic HyperplasiaProstatic NeoplasmsAgedHumansMaleProstateadenocarcinomacase reportmultimodal treatmentPelvic radiotherapyprostate leiomyosarcoma

Identifiers

PMID36578814
PMCPMC9755551
OpenAlexW4312737275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.